Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 5/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409322 | 0.91 | CTSC (0.34) | — | |
| SCHEMBL30656926 | 0.88 | MMP2 (0.40) | BACE1MMP8KISS1RMMP1 | |
| SCHEMBL30495730 | 0.87 | BACE1 (0.41) | BACE1 | |
| SCHEMBL2183538 | 0.87 | NPY4R (0.33) | BACE1KISS1R | |
| SCHEMBL16468661 | 0.86 | CTSC (0.35) | — | |
| SCHEMBL30656920 | 0.86 | NPY4R (0.38) | KISS1RMMP1 | |
| SCHEMBL2194721 | 0.85 | BACE1 (0.36) | BACE1CTSD | |
| SCHEMBL2195079 | 0.84 | ERAP2 (0.49) | MMP8KISS1RMMP1 | |
| SCHEMBL2193343 | 0.83 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL31073567 | 0.83 | BACE1 (0.42) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | BACE1 2543/4885MMP8 1239/4885CTSD 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.