⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21777149 | 0.85 | FKBP5 (0.64) | — | |
| SCHEMBL29848931 | 0.82 | — | — | |
| Trifluoroacetic Acid SCHEMBL29437766 | 0.82 | MMP1 (0.38) | — | |
| SCHEMBL14080856 | 0.74 | CYP1A2 (0.44) | — | |
| SCHEMBL5393702 | 0.72 | — | — | |
| SCHEMBL8535240 | 0.71 | NOTUM (0.68) | — | |
| SCHEMBL2625317 | 0.67 | NOTUM (0.40) | — | |
| SCHEMBL179270 | 0.67 | MMP1 (0.44) | — | |
| SCHEMBL2632725 | 0.67 | — | — | |
| SCHEMBL17459262 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | claimed |
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | claimed |
| EP-4414037-A2 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASES | Nippon Chemiphar Co., Ltd. (JP) | 2024-08-14 | — | — | EP | claimed |
| EP-4396191-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-07-10 | — | — | EP | claimed |
| EP-3513792-B9 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASES | NIPPON CHEMIPHAR CO (JP) | 2024-07-10 | — | — | EP | claimed |
| US-20240156796-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF STRESS-RELATED DISORDERS | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2024-05-16 | — | — | US | claimed |
| EP-3513792-B1 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASES | NIPPON CHEMIPHAR CO (JP) | 2024-03-27 | — | — | EP | claimed |
| EP-4299074-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF STRESS-RELATED DISORDERS | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2024-01-03 | — | — | EP | claimed |
| WO-2023033740-A9 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-12-28 | — | — | WO | claimed |
| CN-117122598-A | Use of morphinan derivatives in the treatment of opioid delta receptor agonist-related diseases | 日本化学药品株式会社 | 2023-11-28 | — | — | CN | claimed |
| EP-3157573-A2 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | Moderna Therapeutics, Inc. (US) | 2017-04-26 | — | — | EP | claimed |
| WO-2015196128-A2 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2015-12-23 | — | — | WO | claimed |
| EP-2320891-A1 | BUTYRYLCHOLINESTERASE LIGANDS AS DIAGNOSTIC TOOLS AND TREATMENT FOR DESEASES OF THE NERVOUS SYSTEM | Treventis Corporation (US) | 2011-05-18 | — | — | EP | claimed |
| WO-2010025368-A1 | BUTYRYLCHOLINESTERASE LIGANDS AS DIAGNOSTIC TOOLS AND TREATMENT FOR DESEASES OF THE NERVOUS SYSTEM | TREVENTIS CORPORATION (US) | 2010-03-04 | — | — | WO | claimed |
| EP-1490064-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | Pharmacia Corporation (US) | 2004-12-29 | — | — | EP | claimed |
| WO-2003068230-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORPORATION (US) | 2003-08-21 | — | — | WO | claimed |
| EP-0145068-B1 | PROCESS FOR THE PREPARATION OF 2-PYRIDONE | STAMICARBON B.V. (NL) | 1987-10-07 | — | — | EP | claimed |
| EP-0123362-B1 | PROCESS FOR THE PREPARATION OF 6-METHYLPYRIDONE-2 | STAMICARBON B.V. (NL) | 1987-08-05 | — | — | EP | claimed |
| US-4639525-A | Process for the preparation of pyridone-2 by demethylation | STAMICARBON B.V. (NL) | 1987-01-27 | — | — | US | claimed |
| EP-0145068-A2 | Process for the preparation of 2-pyridone | STAMICARBON B.V. (NL) | 1985-06-19 | — | — | EP | claimed |