Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.68 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384813 | 0.82 | NOTUM (1.00) | NOTUMMAP2K1GPR84GCKALDH1A1 | |
| SCHEMBL30693692 | 0.82 | NOTUM (0.56) | NOTUMMAP2K1NPY5RGPR84GCK | |
| SCHEMBL8515018 | 0.80 | NOTUM (0.54) | NOTUMMAP2K1NPY5RGPR84CA12 | |
| SCHEMBL5674033 | 0.77 | NOTUM (0.67) | NOTUMMAP2K1GPR84MMP1MMP12 | |
| SCHEMBL11226843 | 0.77 | NOTUM (0.67) | NOTUMMAP2K1NPY5RGCKPIM1 | |
| SCHEMBL7369068 | 0.77 | NOTUM (0.67) | NOTUMMAP2K1CA12CA9MMP1 | |
| SCHEMBL5393702 | 0.76 | — | — | |
| SCHEMBL28606824 | 0.75 | NOTUM (0.48) | NOTUMMAP2K1MMP1MMP12MMP2 | |
| SCHEMBL30602735 | 0.75 | NOTUM (0.53) | NOTUMMAP2K1CA12CA9MMP1 | |
| SCHEMBL5709792 | 0.73 | NOTUM (0.52) | NOTUMNPY5RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118142589-A | Catalyst for co-production of dimethyl oxalate and dimethyl carbonate, preparation method and application thereof | 河南能源集团研究总院有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117996027-A | Lithium-rich manganese-based positive electrode material and preparation method and application thereof | 苏州埃米特材料科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117924171-A | Phenanthrone derivative and synthesis method thereof | 华南理工大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117776958-A | Aromatic hydrocarbon carboxylic acid meta-position alkylation product and synthesis method thereof | 华南理工大学 | 2024-03-29 | — | — | CN | claimed |
| CN-118142589-A | Catalyst for co-production of dimethyl oxalate and dimethyl carbonate, preparation method and application thereof | 河南能源集团研究总院有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118142589-A | Catalyst for co-production of dimethyl oxalate and dimethyl carbonate, preparation method and application thereof | 河南能源集团研究总院有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117996027-A | Lithium-rich manganese-based positive electrode material and preparation method and application thereof | 苏州埃米特材料科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117924171-A | Phenanthrone derivative and synthesis method thereof | 华南理工大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117776958-A | Aromatic hydrocarbon carboxylic acid meta-position alkylation product and synthesis method thereof | 华南理工大学 | 2024-03-29 | — | — | CN | disclosed |
| US-9527066-B2 | Dihydroxybipyridine complexes of ruthenium and iridium for water oxidation and hydrogenation | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527066-B2 | Dihydroxybipyridine complexes of ruthenium and iridium for water oxidation and hydrogenation | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2016-12-27 | — | — | US | disclosed |
| US-20160101177-A1 | pH AND LIGHT ACTIVATED ANTI-CANCER DRUGS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA | 2016-04-14 | — | — | US | disclosed |
| US-9034873-B2 | Pyridazine and pyrrole compounds, processes for obtaining them and uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-05-19 | — | — | US | disclosed |
| US-9034873-B2 | Pyridazine and pyrrole compounds, processes for obtaining them and uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-05-19 | — | — | US | disclosed |
| US-20140219911-A1 | DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140219911-A1 | DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2014-08-07 | — | — | US | disclosed |
| WO-2012070040-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING RENAL DYSFUNCTION INDUCED BY RENAL HYPOPERFUSION OR ACUTE KIDNEY INJURY | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD (IL) | 2012-05-31 | — | — | WO | disclosed |
| US-20100298562-A1 | Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2010-11-25 | — | — | US | disclosed |
| US-20100298562-A1 | Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2010-11-25 | — | — | US | disclosed |
| WO-2008012440-A2 | PYRIDAZINE AND PYRROLE COMPOUNDS, PROCESSES FOR OBTAINING THEM AND USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160101177-A1 | pH AND LIGHT ACTIVATED ANTI-CANCER DRUGS | CA2, CA6, NFATC1 | NOTUM 4320/4885MAP2K1 2138/4885NPY5R 4676/4885 |
| US-20100298562-A1 | Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses | PPOX, PNPO, PLPBP | NOTUM 3196/4885MAP2K1 1890/4885NPY5R 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.