Gilteritinib

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Gilteritinib SCHEMBL29357951	1.00	FLT3 (1.00)	FLT3RETROS1EML4ALK
	Gilteritinib SCHEMBL29432551	0.96	FLT3 (1.00)	FLT3RETROS1EML4ALK
	Gilteritinib SCHEMBL29355822	0.96	FLT3 (1.00)	FLT3RETROS1EML4ALK
	Gilteritinib SCHEMBL282229	0.96	FLT3 (1.00)	FLT3RETROS1EML4ALK
	SCHEMBL328303	0.93	FLT3 (0.94)	FLT3RETROS1EML4ALK
	SCHEMBL29157675	0.92	FLT3 (0.92)	FLT3RETROS1EML4ALK
	Gilteritinib SCHEMBL22684910	0.91	FLT3 (0.91)	FLT3RETROS1EML4ALK
	Gilteritinib SCHEMBL22684912	0.91	FLT3 (0.91)	FLT3RETROS1EML4ALK
	SCHEMBL22652336	0.90	FLT3 (0.89)	FLT3RETROS1EML4ALK
	SCHEMBL21455071	0.90	FLT3 (0.89)	FLT3RETROS1EML4ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.