N-Benzylaniline

N-Benzylaniline

SCHEMBL21820163

O=[N+]([O-])c1ccc(Cc2ccncc2)cc1.c1ccc(CNc2ccccc2)cc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPRF P10586 1/20 0.74
PTPN2 P17706 1/20 0.74
PTPN1 P18031 1/20 0.74
PTPN11 Q06124 1/20 0.74
POLB P06746 3/20 0.66
MAPT P10636 6/20 0.60
ALDH1A1 P00352 5/20 0.57
MAPK1 P28482 1/20 0.57
MPI P34949 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 2/20 0.51
MEN1 O00255 2/20 0.51
LMNA P02545 2/20 0.50
HPGD P15428 1/20 0.48
ATM Q13315 1/20 0.48
F2 P00734 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL627885 0.86 PTPRF (1.00) PTPRFPTPN2PTPN1PTPN11POLB
SCHEMBL3158234 0.83 PTPRF (0.87) PTPRFPTPN2PTPN1PTPN11POLB
SCHEMBL177812 0.81 POLB (1.00) POLBMAPTALDH1A1MAPK1MPI
SCHEMBL4953680 0.78 PTPRF (0.83) PTPRFPTPN2PTPN1PTPN11MAPT
SCHEMBL522061 0.78 KCNH3 (0.68) KMT2AMEN1F2
SCHEMBL267666 0.78 ALDH1A1 (0.70) PTPRFPTPN2PTPN1PTPN11POLB
SCHEMBL2356855 0.77 POLB (0.71) PTPRFPTPN2PTPN1PTPN11POLB
SCHEMBL6699468 0.75 PTPRF (0.78) PTPRFPTPN2PTPN1PTPN11POLB
SCHEMBL27404099 0.75 POLB (0.86) POLBMAPTALDH1A1MAPK1MPI
Perchlorate SCHEMBL11651402 0.75 POLB (0.86) POLBMAPTALDH1A1MAPK1MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200086318-A1 SYSTEM AND METHOD FOR CREATING QUANTIFIABLE SIGNALS UCHICAGO ARGONNE, LLC 2020-03-19 US disclosed