Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283543 | 0.94 | THRB (0.38) | TRPV1RAF1SOS1KCNH2 | |
| SCHEMBL21821318 | 0.90 | TRPV1 (0.36) | TRPV1RAF1ITGA5ITGB6ITGB8 | |
| SCHEMBL19283643 | 0.87 | ITGA5 (0.43) | TRPV1ITGA5ITGB6ITGB8KCNH2 | |
| SCHEMBL19283649 | 0.82 | TRPV1 (0.39) | TRPV1CNR2ITGA5ITGB6ITGB8 | |
| SCHEMBL19283607 | 0.81 | ITGA5 (0.43) | RAF1ITGA5ITGB6ITGB8SOS1 | |
| SCHEMBL21821295 | 0.79 | ITGA5 (0.47) | RAF1ITGA5ITGB6ITGB8SOS1 | |
| SCHEMBL21821294 | 0.77 | ITGA5 (0.42) | RAF1ITGA5ITGB6ITGB8SOS1 | |
| SCHEMBL19283573 | 0.77 | ITGA5 (0.44) | RAF1ITGA5ITGB6ITGB8MAPK14 | |
| SCHEMBL21821320 | 0.76 | ITGA5 (0.42) | RAF1ITGA5ITGB6ITGB8SOS1 | |
| SCHEMBL23522701 | 0.76 | L3MBTL1 (0.44) | TRPV1KCNH2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419973-B1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2020-04-08 | — | — | EP | claimed |