Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.42 |
| ▸ | CTSA | P10619 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301144 | 0.88 | FAAH (0.41) | L3MBTL1TRPV1CTSAGAAMEN1 | |
| SCHEMBL19300952 | 0.83 | L3MBTL1 (0.46) | L3MBTL1TRPV1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL19301092 | 0.82 | L3MBTL1 (0.45) | L3MBTL1TRPV1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL20743185 | 0.79 | GAA (0.45) | L3MBTL1CTSAATMGAAMEN1 | |
| SCHEMBL19301143 | 0.79 | FAAH (0.41) | L3MBTL1CTSAATMGAAMEN1 | |
| SCHEMBL23522702 | 0.78 | L3MBTL1 (0.41) | L3MBTL1CTSAMEN1ALDH1A1POLB | |
| SCHEMBL19283643 | 0.78 | ITGA5 (0.43) | L3MBTL1TRPV1SMN1; SMN2KCNH2 | |
| SCHEMBL3447133 | 0.78 | MAPT (0.46) | L3MBTL1CTSAATMMEN1ALDH1A1 | |
| SCHEMBL3596702 | 0.78 | KCNQ3 (0.54) | L3MBTL1CTSAATMMEN1ALDH1A1 | |
| SCHEMBL3447481 | 0.78 | KCNQ3 (0.54) | L3MBTL1CTSAATMMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188804-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2021-06-24 | — | — | US | disclosed |
| CN-109153667-B | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2021-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188804-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | KCNJ2, KCNN2, KCNN1 | L3MBTL1 1670/4885TRPV1 136/4885CTSA 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.