Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008308 | 0.92 | CNR1 (0.42) | CNR1CNR2LPLLIPGMGLL | |
| SCHEMBL4650772 | 0.85 | PTGS2 (0.46) | LPLLIPGMGLLCYP3A4HIF1A | |
| SCHEMBL8018711 | 0.81 | SKP2 (0.44) | CYP3A4CYP2D6HIF1AHSD17B10CA2 | |
| SCHEMBL8020344 | 0.78 | PTGS2 (0.46) | LPLLIPGMGLLCYP3A4HIF1A | |
| SCHEMBL8020842 | 0.78 | PTGS2 (0.46) | LPLLIPGMGLLCYP3A4HIF1A | |
| SCHEMBL8024876 | 0.78 | PTGS2 (0.46) | LPLLIPGMGLLCYP3A4HIF1A | |
| SCHEMBL26882 | 0.75 | TRPA1 (0.40) | LPLLIPGMGLLNPC1MAPT | |
| SCHEMBL8008134 | 0.71 | ESR1 (0.41) | — | |
| SCHEMBL17841792 | 0.69 | ESR1 (0.48) | LPLLIPGMGLLCYP3A4HIF1A | |
| SCHEMBL28113746 | 0.69 | MGLL (0.31) | CNR2LPLLIPGMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001051-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2012-01-05 | — | — | WO | disclosed |