SCHEMBL2182275

SCHEMBL2182275

O[C](c1ccccc1)N1CCCCC1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.63
ALDH1A1 P00352 5/20 0.55
USP2 O75604 1/20 0.55
GAA P10253 1/20 0.53
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HTT P42858 2/20 0.49
CYP2C9 P11712 1/20 0.49
MAPK1 P28482 1/20 0.47
GLA P06280 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27798296 0.81 HPGD (0.63) HPGDALDH1A1USP2GAAMEN1
Bicarbonate SCHEMBL1582960 0.80 HPGD (0.96) HPGDALDH1A1USP2MAPK1
SCHEMBL10777394 0.79 ALDH1A1 (0.67) HPGDALDH1A1GAAMEN1KMT2A
SCHEMBL2462255 0.77 HPGD (0.59) HPGDALDH1A1USP2GAAMEN1
SCHEMBL8919062 0.77 HPGD (1.00) HPGDALDH1A1USP2MAPK1
SCHEMBL243236 0.77 HPGD (1.00) HPGDALDH1A1USP2MAPK1
SCHEMBL436090 0.77 HPGD (1.00) HPGDALDH1A1USP2MAPK1
SCHEMBL3731573 0.77 HPGD (0.59) HPGDALDH1A1USP2GAAMEN1
SCHEMBL1927946 0.77 HPGD (1.00) HPGDALDH1A1USP2MAPK1
SCHEMBL27929296 0.77 HPGD (1.00) HPGDALDH1A1USP2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023192919-A1 EASY FLOW THERMOPLASTIC POLYURETHANE (TPU) BASF SE (DE) 2023-10-05 WO disclosed
EP-3016989-B1 POLYURETHANE BASED ON RENEWABLE RESOURCES BASF SE (DE) 2023-08-09 EP disclosed
US-11124594-B2 Polyurethane based on renewable raw materials BASF SE (DE) 2021-09-21 US disclosed
CN-105143296-B The discoloration of the thermoplastic polyurethane based on polymer polyatomic alcohol is reduced by introducing aliphatic isocyanate 巴斯夫欧洲公司 2018-06-12 CN disclosed
US-9957347-B2 Reduced discoloration of thermoplastic polyurethanes based on polymer polyols via incorporation of aliphatic isocyanates BASF SE (DE) 2018-05-01 US disclosed
US-9920159-B2 2018-03-20 US disclosed
US-20170335047-A1 POLYURETHANE DISPERSIONS BASED ON RENEWABLE RAW MATERIALS BASF SE (DE) 2017-11-23 US disclosed
US-20160152761-A1 POLYURETHANE BASED ON RENEWABLE RAW MATERIALS BASF SE (DE) 2016-06-02 US disclosed
EP-3016989-A1 POLYURETHANE BASED ON RENEWABLE RAW MATERIALS BASF SE (DE) 2016-05-11 EP disclosed
US-20160009851-A1 REDUCED DISCOLORATION OF THERMOPLASTIC POLYURETHANES BASED ON POLYMER POLYOLS VIA INCORPORATION OF ALIPHATIC ISOCYANATES BASF SE (DE) 2016-01-14 US disclosed
CN-105143296-A Reduced discoloration of thermoplastic polyurethanes based on polymer polyols by incorporating aliphatic isocyanates BASF SE 2015-12-09 CN disclosed
WO-2015000722-A1 POLYURETHANE BASED ON RENEWABLE RAW MATERIALS BASF SE (DE) 2015-01-08 WO disclosed
CN-103003360-B Method for producing blends from polylactides (PLA) and thermoplastic polyurethanes (TPU) BASF SE 2014-12-10 CN disclosed
US-8633283-B2 Process for producing blends made of polylactides (PLAS) and of thermoplastic polyurethanes (TPUS) BASF SE (DE) 2014-01-21 US disclosed
EP-2582757-A1 METHOD FOR PRODUCING BLENDS FROM POLYLACTIDES (PLA) AND THERMOPLASTIC POLYURETHANES (TPU) BASF SE (DE) 2013-04-24 EP disclosed
WO-2011157691-A1 METHOD FOR PRODUCING BLENDS FROM POLYLACTIDES (PLA) AND THERMOPLASTIC POLYURETHANES (TPU) BASF SE (DE) 2011-12-22 WO disclosed
US-20110166316-A1 POLYURETHANES BASED ON POLYESTER DIOLS WITH IMPROVED CRYSTALLIZATION BEHAVIOR BASF SE (DE) 2011-07-07 US disclosed