Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 3/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | BHMT | Q93088 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL7747010 | 0.93 | GRIK1 (0.39) | KMT2AALOX15BLMPMP22GRIK1 | |
| SCHEMBL8452313 | 0.82 | ECE1 (0.46) | KMT2AALOX15BLMPMP22ECE1 | |
| SCHEMBL7744529 | 0.82 | ECE1 (0.46) | KMT2AALOX15BLMPMP22ECE1 | |
| Asparagine SCHEMBL366070 | 0.80 | ALOX15 (0.50) | KMT2AALOX15BLMPMP22GRIK1 | |
| Asparagine SCHEMBL7998953 | 0.80 | ALOX15 (0.50) | KMT2AALOX15BLMPMP22GRIK1 | |
| SCHEMBL7744531 | 0.80 | SLC22A6 (0.38) | ECE1 | |
| Asparagine SCHEMBL366069 | 0.80 | ALOX15 (0.50) | KMT2AALOX15BLMPMP22GRIK1 | |
| Asparagine SCHEMBL7998952 | 0.80 | ALOX15 (0.50) | KMT2AALOX15BLMPMP22GRIK1 | |
| Asparagine SCHEMBL10011961 | 0.80 | ALOX15 (0.50) | KMT2AALOX15BLMPMP22GRIK1 | |
| Asparagine SCHEMBL6520765 | 0.78 | ALOX15 (0.48) | KMT2AALOX15BLMPMP22GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220010239-A1 | DETERGENT POLYMER AND COMPOSITION | ITALMATCH CHEMICALS S.P.A. (IT) | 2022-01-13 | — | — | US | disclosed |
| EP-3861093-A1 | DETERGENT POLYMER AND COMPOSITION | Italmatch Chemicals S.p.A. (IT) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020070544-A1 | DETERGENT POLYMER AND COMPOSITION | ITALMATCH CHEMICALS S.P.A. (IT) | 2020-04-09 | — | — | WO | disclosed |