Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL811125 | 0.96 | ALDH1A1 (0.54) | ALDH1A1LMNAHSD17B10TSHRCYP3A4 | |
| Ethyl Acetate SCHEMBL9419114 | 0.95 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10TSHRCYP3A4 | |
| Ethyl Acetate SCHEMBL9063181 | 0.95 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10TSHRCYP3A4 | |
| Ethyl Acetate SCHEMBL27840047 | 0.88 | ALDH1A1 (0.45) | ALDH1A1LMNAHSD17B10TSHRCYP3A4 | |
| SCHEMBL4388901 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRCYP3A4 | |
| SCHEMBL28359555 | 0.83 | TSHR (0.48) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| Toluene SCHEMBL3846761 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| SCHEMBL27419996 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4TDP1MEN1 | |
| Ethyl Acetate SCHEMBL10488295 | 0.82 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Ethyl Pyruvate SCHEMBL29019914 | 0.82 | KMT2A (0.50) | ALDH1A1TSHRCYP3A4TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050792-B1 | METAL NANOPARTICLE DISPERSION AND PRODUCTION PROCESS OF THE SAME | DAINIPPON INK & CHEMICALS (JP) | 2013-11-20 | — | — | EP | disclosed |
| US-8088437-B2 | Method for production of silver-containing nano-structure, and silver-containing nano-structure | DIC CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20100120960-A1 | METHOD FOR PRODUCTION OF SILVER-CONTAINING NANO-STRUCTURE, AND SILVER-CONTAINING NANO-STRUCTURE | DIC CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2147733-A1 | METHOD FOR PRODUCTION OF SILVER-CONTAINING NANO-STRUCTURE, AND SILVER-CONTAINING NANO-STRUCTURE | DIC Corporation (JP) | 2010-01-27 | — | — | EP | disclosed |
| US-20090198009-A1 | METAL NANOPARTICLE DISPERSION AND PRODUCTION PROCESS OF THE SAME | DIC CORPORATION (JP) | 2009-08-06 | — | — | US | disclosed |
| EP-2050792-A1 | METAL NANOPARTICLE DISPERSION AND PROCESS FOR PRODUCING THE SAME | DIC Corporation (JP) | 2009-04-22 | — | — | EP | disclosed |