SCHEMBL4388901

SCHEMBL4388901

CC(=O)OCO.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TDP1 Q9NUW8 2/20 0.46
CYP3A4 P08684 1/20 0.46
ESR1 P03372 3/20 0.42
ESR2 Q92731 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.37
ELANE P08246 2/20 0.36
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
SLC18A3 Q16572 2/20 0.36
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
HMGB1 P09429 1/20 0.35
GGT1 P19440 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL218280 0.85 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4ESR1ESR2
Ethyl Acetate SCHEMBL811125 0.85 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4ESR1ESR2
Ethyl Acetate SCHEMBL9063181 0.83 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4ESR1ESR2
Ethyl Acetate SCHEMBL9419114 0.83 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4ESR1ESR2
Acetic Acid Methyl Ester SCHEMBL19208995 0.79 TDP1 (0.55) ALDH1A1TDP1CYP3A4ESR1ESR2
SCHEMBL23581251 0.79 CYP3A4 (0.50) ALDH1A1TDP1CYP3A4ESR1ESR2
Acetic Acid SCHEMBL9549791 0.79 ALDH1A1 (0.44) ALDH1A1TDP1CYP3A4ESR1ESR2
Acetic Acid SCHEMBL6135660 0.79 CYP3A4 (0.67) ALDH1A1TDP1CYP3A4ESR1ESR2
Acetic Acid SCHEMBL158139 0.79 CYP3A4 (0.67) ALDH1A1TDP1CYP3A4ESR1ESR2
Acetic Acid SCHEMBL7629010 0.79 CYP3A4 (0.67) ALDH1A1TDP1CYP3A4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629431-B2 Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate IDEMITSU KOSAN CO., LTD. (JP) 2009-12-08 US disclosed
US-20080064847-A1 Oxidative carbonylation; molecular weight control IDEMISU KOSAN CO., LTD. (JP) 2008-03-13 US disclosed