SCHEMBL2182880

SCHEMBL2182880

CNC(=O)Oc1ccc(C)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 2/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
MMP13 P45452 1/20 0.53
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
GAA P10253 1/20 0.44
ACHE P22303 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12893245 0.91 ALDH1A1 (0.51) LMNAALDH1A1KDM4ENPC1RAB9A
SCHEMBL15167068 0.89 ALDH1A1 (0.54) LMNAALDH1A1KDM4ENPC1RAB9A
Phenyl Methylcarbamate SCHEMBL27797560 0.86 CYP1A2 (0.51) LMNAALDH1A1KDM4ENPC1RAB9A
SCHEMBL9326191 0.83 SMN1; SMN2 (0.59) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL27513052 0.83 KDM4E (0.53) LMNAALDH1A1KDM4ENPC1RAB9A
SCHEMBL11675308 0.81 TDP1 (0.56) LMNAALDH1A1KDM4ENPC1RAB9A
SCHEMBL11599136 0.81 ALDH1A1 (0.45) LMNAALDH1A1KDM4ENPC1RAB9A
SCHEMBL2540440 0.81 ALDH1A1 (0.45) LMNAALDH1A1KDM4ENPC1RAB9A
SCHEMBL20820013 0.81 MGLL (0.54) LMNAALDH1A1KDM4ENPC1RAB9A
SCHEMBL6924040 0.81 ALDH1A1 (0.51) LMNAALDH1A1KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3877365-A1 SUBSTITUTED TOLYL AS FUNGICIDES FMC CORPORATION (US) 2021-09-15 EP claimed
CN-103562198-B There is muscarinic receptor antagonist and the compound of beta 2-adrenergic receptor agonists activity 奇斯药制品公司 2016-08-24 CN claimed
CN-103562198-A Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity CHIESI FARMA SPA 2014-02-05 CN claimed
CN-1239865-A Insecticidal and acaricidal composition AMERICAN CYANAMID CO (US) 1999-12-29 CN claimed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
WO-2023081854-A1 AKT3 MODULATORS GEORGIAMUNE LLC (US) 2023-05-11 WO disclosed
WO-2023081845-A1 AKT3 MODULATORS GEORGIAMUNE LLC (US) 2023-05-11 WO disclosed
EP-2931316-B1 HYDROXYL-POLYMER-DRUG-PROTEIN CONJUGATES MERSANA THERAPEUTICS INC (US) 2019-02-20 EP disclosed
EP-3228325-A1 PROTEIN-POLYMER-DRUG CONJUGATES Mersana Therapeutics, Inc. (US) 2017-10-11 EP disclosed
CN-105794825-A Insecticide composition containing tetrachlorantraniliprole and carbamic acid esters 陕西汤普森生物科技有限公司 2016-07-27 CN disclosed
CN-102657209-B The insect-killing composition of a kind of fluorine-containing lice sulfanilamide (SN) and amino formate 陕西韦尔奇作物保护有限公司 2016-06-08 CN disclosed
US-5614498-A OLIGOPEPTIDES, BRONCHDILATORS BANYU PHARMACEUTICAL CO., LTD. (JP) 1997-03-25 US disclosed
US-5496928-A Endothelin antagonistic substance BANYU PHARMACEUTICAL CO., LTD. (JP) 1996-03-05 US disclosed
US-5365691-A Methods and agents for combating cockroaches BAYER AKTIENGESELLSCHAFT (DE) 1994-11-22 US disclosed
EP-0555537-A2 Endothelin antagonistic substance BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-18 EP disclosed
EP-0135714-B1 SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS MELAMINE CHEMICALS, INC. (US) 1991-11-06 EP disclosed
CN-87104900-A New suspension-type pesticide formulation 1988-01-27 CN disclosed
US-4692550-A Continuous process for thermal splitting of carbamic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-3938986-A ISOPROPYL N-PHENYLCARBAMATE OR ISOPROPYL N-(3-CHLOROPHENYL)CARBAMATE AND 4-CHLOROPHENYL N-METHYLCARBAMATE PPG INDUSTRIES, INC. (US) 1976-02-17 US disclosed