Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24004518 | 0.91 | KMT2A (0.64) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21828972 | 0.85 | MAPT (0.61) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21828976 | 0.82 | MAPT (0.60) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL24004566 | 0.82 | GRIK1 (0.61) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21829030 | 0.81 | NPC1 (0.68) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21829023 | 0.80 | KMT2A (0.78) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29124110 | 0.80 | NPC1 (1.00) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12468557 | 0.78 | AVPR2 (0.75) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21828987 | 0.77 | MAPT (0.69) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL17149669 | 0.76 | KMT2A (0.64) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210347752-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | BARUCH S. BLUMBERG INSTITUTE | 2021-11-11 | — | — | US | claimed |
| CN-112888688-A | Benzamide derivatives as CGAS-STING pathway agonists | 巴鲁克斯布伦博格研究所 | 2021-06-01 | — | — | CN | claimed |
| WO-2020072492-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | BARUCH S. BLUMBERG INSTITUTE (US) | 2020-04-09 | — | — | WO | claimed |
| US-12509436-B2 | Benzamide derivatives as cGAS-sting pathway agonists | BARUCH S. BLUMBERG INSTITUTE (US) | 2025-12-30 | — | — | US | disclosed |
| US-20210347752-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | BARUCH S. BLUMBERG INSTITUTE | 2021-11-11 | — | — | US | disclosed |
| US-20210347752-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | BARUCH S. BLUMBERG INSTITUTE | 2021-11-11 | — | — | US | disclosed |
| CN-112888688-A | Benzamide derivatives as CGAS-STING pathway agonists | 巴鲁克斯布伦博格研究所 | 2021-06-01 | — | — | CN | disclosed |
| WO-2020072492-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | BARUCH S. BLUMBERG INSTITUTE (US) | 2020-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509436-B2 | Benzamide derivatives as cGAS-sting pathway agonists | STING1, CGAS, IFNAR1 | KMT2A 3963/4885NPC1 633/4885RAB9A 370/4885 |
| US-20210347752-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | STING1, CGAS, MAVS | KMT2A 2676/4885NPC1 1661/4885RAB9A 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.