Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 7/20 | 0.33 |
| ▸ | GRPR | P30550 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186474 | 0.85 | CTSC (0.37) | CTSCBACE1 | |
| SCHEMBL20397445 | 0.85 | FNTA (0.37) | CTSDBACE1CASP3CASP7 | |
| SCHEMBL31049654 | 0.85 | CTSD (0.38) | CTSDBACE1CASP3CASP7 | |
| SCHEMBL20397476 | 0.85 | FNTA (0.37) | CTSDBACE1CASP3CASP7 | |
| SCHEMBL16468413 | 0.84 | CTSL (0.46) | — | |
| SCHEMBL29881377 | 0.83 | CTSD (0.35) | CTSCCTSDBACE1CASP3CASP7 | |
| SCHEMBL5499034 | 0.82 | CTSC (0.42) | CTSC | |
| SCHEMBL9012496 | 0.82 | CTSC (0.42) | CTSC | |
| SCHEMBL3750881 | 0.82 | MME (0.41) | — | |
| SCHEMBL3750892 | 0.82 | MME (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | CTSC 331/4885CTSD 1192/4885BACE1 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.