SCHEMBL2183129

SCHEMBL2183129

C[C@@]1(C(=O)O)NCCC1O

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.34
TP53 P04637 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
THPO P40225 1/20 0.34
STAT6 P42226 1/20 0.34
HIF1A Q16665 1/20 0.34
NPC1 O15118 1/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
MTOR P42345 1/20 0.34
RAB9A P51151 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18689833 1.00 MAPK1 (0.34) MAPK1TP53NFKB1CYP2C19THPO
SCHEMBL25350207 0.80 MAPK1 (0.35) MAPK1TP53NFKB1CYP2C19THPO
SCHEMBL13125471 0.78 KMT2A (0.31)
SCHEMBL973477 0.78 KMT2A (0.31)
SCHEMBL10594225 0.77 MAPK1 (0.33) MAPK1TP53NFKB1CYP2C19THPO
SCHEMBL7749544 0.74 MAPK1 (0.31) MAPK1TP53NFKB1CYP2C19THPO
SCHEMBL7331670 0.73 GABRP (0.31) PMP22
Hydrochloric Acid SCHEMBL7748835 0.72 MAPK1 (0.31) MAPK1TP53NFKB1CYP2C19THPO
Hydrochloric Acid SCHEMBL25353864 0.71
SCHEMBL5203785 0.71 LMNA (0.37) CYP2C19HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112347-A4 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING CO (US) 2004-09-29 EP claimed
EP-1206524-A4 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING CO (US) 2004-09-29 EP claimed
US-6764854-B2 PROPAGATING PLANTS; OBTAIN SPORE, EXPOSE TO STRESS, INCUBATE WITH INDUCER, RECOVER AND CULTURE SPORE NORTHWEST PLANT BREEDING COMPANY 2004-07-20 US claimed
US-20020151057-A1 Methods for generating doubled haploid maize plants NORTHWEST PLANT BREEDING CO. 2002-10-17 US claimed
US-20020104128-A1 Methods for generating doubled haploid plants NORTHWEST PLANT BREEDING COMPANY 2002-08-01 US claimed
WO-2002052926-A2 METHODS FOR GENERATING DOUBLED HAPLOID MAIZE PLANTS NORTHWEST PLANT BREEDING CO. (US) 2002-07-11 WO claimed
EP-1206524-A2 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS Northwest Plant Breeding Co. (US) 2002-05-22 EP claimed
US-6362393-B1 Methods for generating doubled haploid plants NORTHWEST PLANT BREEDING COMPANY 2002-03-26 US claimed
EP-1112347-A1 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS Northwest Plant Breeding Co. (US) 2001-07-04 EP claimed
WO-2001014518-A2 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING CO. (US) 2001-03-01 WO claimed
WO-2000014202-A1 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING COMPANY (US) 2000-03-16 WO claimed
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP disclosed
WO-2024227957-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2024-11-07 WO disclosed
CN-116874584-A Insulin analogues 犹他大学研究基金会 2023-10-13 CN disclosed
CN-110072884-B Insulin analogues 犹他大学研究基金会 2023-07-28 CN disclosed
US-6362393-B1 Methods for generating doubled haploid plants NORTHWEST PLANT BREEDING COMPANY 2002-03-26 US disclosed
EP-1112347-A1 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS Northwest Plant Breeding Co. (US) 2001-07-04 EP disclosed
WO-2001014518-A2 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING CO. (US) 2001-03-01 WO disclosed
WO-2000014202-A1 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING COMPANY (US) 2000-03-16 WO disclosed
US-5614213-A TRANSDERMAL, SIDE EFFECT REDUCTION ENTEC GESELLSCHAFT FUER ENDOKRINOLOGISCHE TECHNOLOGIE M.B.H. (DE) 1997-03-25 US disclosed