Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18689833 | 0.73 | MAPK1 (0.34) | PMP22 | |
| SCHEMBL2183129 | 0.73 | MAPK1 (0.34) | PMP22 | |
| SCHEMBL7972172 | 0.71 | — | — | |
| SCHEMBL7278062 | 0.69 | — | — | |
| SCHEMBL9675102 | 0.67 | CYP1A2 (0.34) | TSHR | |
| SCHEMBL5961850 | 0.65 | — | — | |
| SCHEMBL3578698 | 0.62 | SLC6A1 (0.32) | TSHR | |
| SCHEMBL24069841 | 0.62 | — | — | |
| SCHEMBL18048096 | 0.60 | ARG1 (0.32) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL10424405 | 0.60 | MAPK1 (0.31) | GABRPGABRDGABRA1TSHRGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413277-B1 | Peptide antagonists of bradykinin | HOECHST AG (DE) | 1994-11-23 | — | — | EP | claimed |
| US-5712417-A | Inhibitors of retroviral proteases | ABBOTT LABORATORIES (US) | 1998-01-27 | — | — | US | disclosed |
| US-5686421-A | INHIBITING PLATELET AGGREGATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-11 | — | — | US | disclosed |
| US-5681838-A | ALSO FOR SUPPRESSING CANCER CELL METASTASES AND BINDING OF OSTEOCLASTS TO BONE SURFACES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |
| US-5663139-A | VIRICIDE OLIGOPEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-02 | — | — | US | disclosed |
| US-5648333-A | POLYPEPTIDES FOR ANTIINFLAMMATORY AGENTS, WOUND HEALING AGENTS, ANTIALLERGENS OR CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |
| US-5629431-A | Inhibitors of retroviral proteases | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-13 | — | — | US | disclosed |
| US-5554594-A | ANTICOAGULANTS, ANTIMETASTASIS AGENTS | CASSELLA AKTIENGESSELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| US-5519113-A | Process for the diastereoselective reductive pinacol coupling of homochiral α-aminoaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |
| US-5463124-A | Treating with niobium trichloride-dimethoxyethane complex and simultaneously controlling all four corners of chirality | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| US-5424293-A | Anticoagulants of platelet aggregation; osteoclast antagonist for treating osteoporosis | CASSELLA AG (DE) | 1995-06-13 | — | — | US | disclosed |
| US-5397796-A | Inhibitors of platelet aggregation, metastasis of carcinoma cells and osteoclast binding to the bone surfaces | CASSELLA AG (DE) | 1995-03-14 | — | — | US | disclosed |
| US-5389614-A | Anticoagulants | CASSELLA AG (DE) | 1995-02-14 | — | — | US | disclosed |
| US-5326875-A | Alkylation of azaglycine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |