SCHEMBL21831566

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5840583	0.81	CYP3A4 (0.38)	LPLLIPGP2RX7HIF1AALDH1A1
	SCHEMBL15130343	0.79	CYP3A4 (0.39)	LPLLIPGP2RX7CA1CA2
	SCHEMBL10269418	0.79	LPL (0.39)	LPLLIPGP2RX7CA1CA2
	SCHEMBL23716967	0.78	LIPG (0.42)	LPLLIPGP2RX7TDP1CA1
	SCHEMBL13139651	0.76	MAPT (0.45)	TDP1MEN1CYP3A4KMT2A
	SCHEMBL22655171	0.76	SELL (0.37)	LPLLIPGP2RX7TDP1HIF1A
	SCHEMBL30412775	0.76	SELL (0.37)	LPLLIPGP2RX7TDP1HIF1A
	SCHEMBL28628663	0.76	LPL (0.44)	LPLLIPGHIF1ACA1CA2
	SCHEMBL16426120	0.76	LPL (0.44)	LPLLIPGP2RX7HIF1ACA1
	SCHEMBL31200686	0.75	CYP3A4 (0.44)	HIF1ACA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.