SCHEMBL218330

SCHEMBL218330

C=COCCCCOC(=O)CCC(=O)OCCCCOC=C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.45
ALDH1A1 P00352 3/20 0.45
CYP3A4 P08684 1/20 0.45
HTR2C P28335 1/20 0.42
ADRA2A P08913 1/20 0.40
ADRA1A P35348 1/20 0.40
MAPT P10636 1/20 0.39
BLM P54132 1/20 0.39
NAAA Q02083 1/20 0.38
DGKA P23743 1/20 0.38
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
RAD52 P43351 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15845115 0.98 TSHR (0.48) TSHRALDH1A1CYP3A4HTR2CADRA2A
SCHEMBL15845183 0.98 TSHR (0.48) TSHRALDH1A1CYP3A4HTR2CADRA2A
SCHEMBL15844685 0.96 TSHR (0.40) TSHRALDH1A1CYP3A4HTR2CADRA2A
SCHEMBL1130528 0.94 TSHR (0.43) TSHRALDH1A1CYP3A4HTR2CADRA2A
SCHEMBL218168 0.94 DGKA (0.45) TSHRALDH1A1CYP3A4HTR2CADRA2A
SCHEMBL2193178 0.92 NPC1 (0.40) TSHRALDH1A1CYP3A4HTR2CADRA2A
Succinic Acid SCHEMBL31375868 0.92 NPC1 (0.40) TSHRALDH1A1CYP3A4HTR2CADRA2A
SCHEMBL17026005 0.92 DGKA (0.48) TSHRALDH1A1CYP3A4HTR2CNAAA
SCHEMBL15844796 0.92 DGKA (0.48) TSHRALDH1A1CYP3A4HTR2CNAAA
SCHEMBL15844859 0.92 DGKA (0.48) TSHRALDH1A1CYP3A4HTR2CNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12098298-B2 Ultra-fast UV-cured material for repairing surface imperfections ILLINOIS TOOL WORKS INC. (US) 2024-09-24 US claimed
EP-3158012-B1 FIRE-RESISTANT COMPOUND AND ITS UTILISATION HILTI AG (LI) 2020-02-19 EP claimed
US-10287504-B2 Composition that forms an insulating layer and use thereof HILTI AKTIENGESELLSCHAFT (LI) 2019-05-14 US claimed
US-9822326-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-11-21 US claimed
WO-2017009301-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2017-01-19 WO claimed
US-9422498-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-08-23 US claimed
US-20150299578-A1 COMPOSITION THAT FORMS AN INSULATING LAYER AND USE THEREOF HILTI AKTIENGESELLSCHAFT (LI) 2015-10-22 US claimed
WO-2015153004-A2 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-08 WO claimed
WO-2015153023-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-08 WO claimed
US-20150275127-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-01 US claimed
WO-2009141444-A1 SURFACE-PROMOTED CURE OF ONE-PART CATIONICALLY CURABLE COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2009-11-26 WO claimed
US-20090288769-A1 Surface-Promoted Cure of Cationically Curable Compositions Comprising Vinyl Ethers LOCTITE (R&D)LIMITED (IE) 2009-11-26 US claimed
US-20080160404-A1 Gel polymer electrolyte precursor and rechargeable cell comprising the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-07-03 US claimed
US-6916890-B1 Thermally reworkable epoxy resins and compositions based thereon HENKEL CORPORATION (US) 2005-07-12 US claimed
US-6706779-B2 Radiation curable compositions containing alkenyl ether functional polyisobutylenes DOW CORNING CORPORATION 2004-03-16 US claimed
US-6703433-B1 LOW CURE ENERGY, VAPOR BARRIERS, DAMPING, HIGH REFRACTIVE INDEX; CORROSION RESISTANCE, TOUGHNESS, TENSILE STRENGTH DOW CORNING CORPORATION 2004-03-09 US claimed
WO-2003031492-A1 THERMALLY REWORKABLE EPOXY RESINS AND COMPOSITIONS BASED THEREO N HENKEL CORPORATION (US) 2003-04-17 WO claimed
EP-1297040-A1 RADIATION CURABLE COMPOSITIONS CONTAINING ALKENYL ETHER FUNCTIONAL POLYISOBUTYLENES Dow Corning Corporation (US) 2003-04-02 EP claimed
US-20020028303-A1 Radiation curable compositions containing alkenyl ether functional polyisobutylenes DOW CORNING CORPORATION CO1232 2002-03-07 US claimed
WO-2001088003-A1 RADIATION CURABLE COMPOSITIONS CONTAINING ALKENYL ETHER FUNCTIONAL POLYISOBUTYLENES DOW CORNING CORPORATION (US) 2001-11-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150275127-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS SBK1, BRSK1, BRSK2 TSHR 3982/4885ALDH1A1 4143/4885CYP3A4 2257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.