Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193178 | 1.00 | NPC1 (0.40) | NPC1ALDH1A1TSHRCYP3A4HTR2C | |
| SCHEMBL218330 | 0.92 | TSHR (0.45) | ALDH1A1TSHRCYP3A4HTR2CHTT | |
| SCHEMBL792729 | 0.91 | ALDH1A1 (0.46) | NPC1ALDH1A1TSHRCYP3A4LMNA | |
| SCHEMBL2199638 | 0.91 | NPC1 (0.46) | NPC1ALDH1A1TSHRCYP3A4LMNA | |
| SCHEMBL15845183 | 0.90 | TSHR (0.48) | ALDH1A1TSHRCYP3A4HTR2CLMNA | |
| SCHEMBL15845115 | 0.90 | TSHR (0.48) | ALDH1A1TSHRCYP3A4HTR2CLMNA | |
| SCHEMBL28933725 | 0.89 | ALDH1A1 (0.48) | NPC1ALDH1A1TSHRCYP3A4LMNA | |
| SCHEMBL581193 | 0.89 | LMNA (0.38) | NPC1ALDH1A1TSHRLMNAADRA2A | |
| SCHEMBL15844685 | 0.88 | TSHR (0.40) | ALDH1A1TSHRCYP3A4HTR2CHTT | |
| SCHEMBL1130528 | 0.86 | TSHR (0.43) | NPC1ALDH1A1TSHRCYP3A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677597-A | Method for producing an optical effect layer comprising magnetic or magnetizable pigment particles and exhibiting more than one marking | 锡克拜控股有限公司 | 2025-03-21 | — | — | CN | disclosed |