Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21833718 | 1.00 | DRD2 (0.36) | DRD2DRD4DRD3CYP19A1LMNA | |
| SCHEMBL18550781 | 1.00 | DRD2 (0.36) | DRD2DRD4DRD3CYP19A1LMNA | |
| SCHEMBL18550982 | 0.79 | CYP19A1 (0.34) | CYP19A1LMNACYP3A4CYP2C9MAPK1 | |
| SCHEMBL21916428 | 0.79 | CYP19A1 (0.34) | CYP19A1LMNACYP3A4CYP2C9MAPK1 | |
| SCHEMBL13677448 | 0.78 | CYP19A1 (0.36) | DRD3CYP19A1LMNACYP3A4CYP2C9 | |
| SCHEMBL13677475 | 0.71 | CYP19A1 (0.40) | CYP19A1LMNACYP3A4CYP2C9MAPK1 | |
| SCHEMBL4266335 | 0.71 | CYP19A1 (0.40) | CYP19A1LMNACYP3A4CYP2C9MAPK1 | |
| SCHEMBL2585385 | 0.71 | CYP19A1 (0.40) | CYP19A1LMNACYP3A4CYP2C9MAPK1 | |
| SCHEMBL23273202 | 0.67 | OAT (0.42) | CYP19A1LMNACYP3A4CYP2C9MAPK1 | |
| SCHEMBL399295 | 0.66 | CYP19A1 (0.37) | CYP19A1LMNACYP3A4CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200101068-A1 | Heteroaryl Derivatives as PARP Inhibitors | LUPIN LIMITED (IN) | 2020-04-02 | — | — | US | disclosed |
| US-20200101068-A1 | Heteroaryl Derivatives as PARP Inhibitors | LUPIN LIMITED (IN) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200101068-A1 | Heteroaryl Derivatives as PARP Inhibitors | PARP1, PARP2, PARP3 | DRD2 2007/4885DRD4 3481/4885DRD3 2148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.