Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834551 | 0.91 | GRM1 (0.57) | NPC1RAB9AALOX15GRM1UCHL1 | |
| SCHEMBL21834637 | 0.86 | NPC1 (0.51) | NPC1RAB9AALOX15GRM1GFER | |
| SCHEMBL21834575 | 0.85 | RAB9A (0.46) | NPC1RAB9AALOX15GRM1GFER | |
| SCHEMBL21834566 | 0.85 | RAB9A (0.47) | NPC1RAB9AALOX15GRM1UCHL1 | |
| SCHEMBL21834549 | 0.84 | GRM1 (0.52) | NPC1RAB9AALOX15GRM1UCHL1 | |
| SCHEMBL21834574 | 0.83 | SMN1; SMN2 (0.45) | NPC1RAB9AALOX15GRM1UCHL1 | |
| SCHEMBL21834679 | 0.82 | RAB9A (0.43) | NPC1RAB9AALOX15GRM1UCHL1 | |
| SCHEMBL21834611 | 0.81 | FFAR2 (0.41) | NPC1RAB9AALOX15GRM1UCHL1 | |
| SCHEMBL21834645 | 0.81 | NPC1 (0.54) | NPC1RAB9AALOX15GRM1UCHL1 | |
| SCHEMBL21834701 | 0.80 | SMN1; SMN2 (0.44) | NPC1RAB9AALOX15GRM1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |