Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834561 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNAGRM1 | |
| SCHEMBL21834635 | 0.88 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNAENPP2 | |
| SCHEMBL21834637 | 0.86 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNAGRM1 | |
| SCHEMBL21834643 | 0.85 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL21834551 | 0.85 | GRM1 (0.57) | NPC1RAB9ASMN1; SMN2LMNAGRM1 | |
| SCHEMBL21834580 | 0.84 | KMT2A (0.49) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL21834646 | 0.84 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL21834566 | 0.83 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2LMNAGRM1 | |
| SCHEMBL21834701 | 0.81 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2LMNAGRM1 | |
| SCHEMBL21834573 | 0.81 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |