Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CD74 | P04233 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21205949 | 0.81 | LTA4H (0.44) | ALDH1A1RAB9AL3MBTL1LTA4HMKNK1 | |
| SCHEMBL21812750 | 0.80 | HDAC3 (0.50) | ALDH1A1RAB9AL3MBTL1LTA4HMKNK1 | |
| SCHEMBL2361567 | 0.80 | LTA4H (0.53) | ALDH1A1RAB9AL3MBTL1LTA4HMKNK1 | |
| Hydrochloric Acid SCHEMBL1930053 | 0.79 | LTA4H (0.51) | ALDH1A1RAB9AL3MBTL1LTA4HMKNK1 | |
| SCHEMBL21206103 | 0.79 | LMNA (0.46) | ALDH1A1RAB9AL3MBTL1LTA4HMKNK1 | |
| SCHEMBL18215350 | 0.77 | MAPK1 (0.56) | ALDH1A1RAB9AL3MBTL1MAPTNPC1 | |
| SCHEMBL21812948 | 0.76 | NAMPT (0.42) | ALDH1A1RAB9AL3MBTL1ROCK1ROCK2 | |
| SCHEMBL21812773 | 0.76 | NAMPT (0.41) | ALDH1A1RAB9AROCK1ROCK2MAPT | |
| SCHEMBL2342868 | 0.76 | CNR2 (0.62) | ALDH1A1RAB9AL3MBTL1MAPTGAA | |
| SCHEMBL21813022 | 0.76 | MEN1 (0.44) | ALDH1A1RAB9AMAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |