Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ATP4A | P20648 | 4/20 | 0.47 |
| ▸ | ATP4B | P51164 | 4/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21834567 | 0.93 | MAPK1 (0.47) | RAB9ANPC1LMNASMN1; SMN2ATP4A | |
| SCHEMBL21834702 | 0.89 | LMNA (0.45) | RAB9ANPC1LMNASMN1; SMN2ATP4A | |
| SCHEMBL21834580 | 0.87 | KMT2A (0.49) | RAB9ANPC1LMNASMN1; SMN2MAPT | |
| SCHEMBL21834645 | 0.84 | NPC1 (0.54) | RAB9ANPC1LMNASMN1; SMN2MAPT | |
| SCHEMBL21834561 | 0.82 | NPC1 (0.49) | RAB9ANPC1LMNASMN1; SMN2MAPT | |
| SCHEMBL21834547 | 0.82 | KMT2A (0.43) | RAB9ANPC1LMNASMN1; SMN2MAPT | |
| SCHEMBL21812611 | 0.82 | ATP4A (0.47) | RAB9ANPC1ATP4AATP4BCXCR1 | |
| SCHEMBL21834637 | 0.81 | NPC1 (0.51) | RAB9ANPC1LMNASMN1; SMN2MAPT | |
| SCHEMBL21834551 | 0.80 | GRM1 (0.57) | RAB9ANPC1LMNASMN1; SMN2MAPT | |
| SCHEMBL21834635 | 0.80 | NPC1 (0.49) | RAB9ANPC1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064175-A1 | INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | ANTABIO SAS (FR) | 2020-04-02 | — | — | WO | disclosed |