Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29147588 | 0.96 | LMNA (0.38) | LMNANPC1RAB9AAPPTHRB | |
| SCHEMBL93485 | 0.93 | NPC1 (0.47) | LMNANPC1RAB9AAPPTHRB | |
| SCHEMBL29358846 | 0.93 | NPC1 (0.47) | LMNANPC1RAB9AAPPTHRB | |
| SCHEMBL28333228 | 0.93 | LMNA (0.38) | LMNANPC1RAB9AAPPTHRB | |
| SCHEMBL29378372 | 0.92 | APP (0.46) | LMNANPC1RAB9AAPPTHRB | |
| SCHEMBL259532 | 0.92 | APP (0.46) | LMNANPC1RAB9AAPPTHRB | |
| SCHEMBL8823408 | 0.89 | LMNA (0.43) | LMNANPC1RAB9AAPPMET | |
| SCHEMBL23121469 | 0.87 | NPC1 (0.44) | LMNANPC1RAB9AAPPTHRB | |
| SCHEMBL373620 | 0.87 | NPC1 (0.45) | LMNANPC1RAB9AAPPMET | |
| SCHEMBL29382102 | 0.87 | NPC1 (0.45) | LMNANPC1RAB9AAPPMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632943-A1 | ACTIVE ENERGY CURABLE RESIN COMPOSITION, HARD COAT LAMINATED FILM, AND FILM FOR APPLICATION TO GLASS | Riken Technos Corporation (JP) | 2020-04-08 | — | — | EP | disclosed |