SCHEMBL29378372

SCHEMBL29378372

C=CC(=O)OCCc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.46
LMNA P02545 3/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
THRB P10828 1/20 0.42
ALOX15 P16050 3/20 0.40
MAPK1 P28482 3/20 0.40
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
CYP3A4 P08684 2/20 0.40
ALOX12 P18054 2/20 0.40
ALOX5 P09917 2/20 0.40
TTR P02766 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
AKR1B10 O60218 1/20 0.40
GMNN O75496 1/20 0.40
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259532 1.00 APP (0.46) APPLMNANPC1RAB9ATHRB
SCHEMBL4195747 0.93 LMNA (0.43) APPLMNANPC1RAB9ATHRB
SCHEMBL29514790 0.93 LMNA (0.43) APPLMNANPC1RAB9ATHRB
SCHEMBL25408635 0.92 LMNA (0.42) APPLMNANPC1RAB9ATHRB
SCHEMBL21836053 0.92 LMNA (0.41) APPLMNANPC1RAB9ATHRB
SCHEMBL29315672 0.91 LMNA (0.41) APPLMNANPC1RAB9ATHRB
SCHEMBL25410461 0.91 LMNA (0.41) APPLMNANPC1RAB9ATHRB
SCHEMBL29437191 0.91 APP (0.41) APPLMNANPC1RAB9ATHRB
SCHEMBL29147588 0.88 LMNA (0.38) APPLMNANPC1RAB9ATHRB
SCHEMBL2777937 0.88 NPC1 (0.47) LMNANPC1RAB9ATHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287232-A1 BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS ADAPTILENS, LLC 2024-08-29 US claimed
US-20250277078-A1 TRI-ARM STAR BOTTLEBRUSH POLYMER WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS DUKE UNIVERSITY (US) 2025-09-04 US disclosed
WO-2024074814-A9 COMPOSITION COMPRISING A FUNCTIONALISED DYE AND A DIALLYLAMINE COMONOMER AND USE THEREOF SUBLINO LIMITED (GB) 2025-05-22 WO disclosed
CN-120019101-A Polycarbonate copolymer and molded article comprising the same 帝人株式会社 2025-05-16 CN disclosed
CN-119998398-A Aromatic polycarbonate resin composition and molded article thereof 帝人株式会社 2025-05-13 CN disclosed
CN-119365538-A Polycarbonate resin composition and molded article comprising the same 帝人株式会社 2025-01-24 CN disclosed
CN-119213077-A Composition and article 大金工业株式会社 2024-12-27 CN disclosed
CN-118922495-A Aromatic polycarbonate resin composition and molded article thereof 帝人株式会社 2024-11-08 CN disclosed
CN-114450375-B Adhesive composition 住友化学株式会社 2024-10-25 CN disclosed
CN-118786166-A Resin composition for fiber-reinforced composite molded article, and fiber-reinforced composite molded article 帝人株式会社 2024-10-15 CN disclosed
CN-114450375-A Adhesive composition 住友化学株式会社 2022-05-06 CN disclosed
CN-110546172-B Ultraviolet absorbing coating material and film coated with the same 新中村化学工业株式会社 2022-04-15 CN disclosed
WO-2022075328-A1 POLYCARBONATE RESIN COMPOSITION AND CIRCUIT MOLDED ARTICLE FOR COMMUNICATION DEVICES 帝人株式会社 2022-04-14 WO disclosed
WO-2022071139-A1 COMPOSITION FOR THREE-DIMENSIONAL SHAPING AND THREE-DIMENSIONAL SHAPED OBJECT ダイキン工業株式会社 2022-04-07 WO disclosed
WO-2022071142-A1 INSULATED ELECTRICAL WIRE AND RESIN COMPOSITION ダイキン工業株式会社 2022-04-07 WO disclosed
WO-2022071144-A1 POWDER COMPOSITION, COATING FILM, AND THREE-DIMENSIONAL SHAPED ARTICLE ダイキン工業株式会社 2022-04-07 WO disclosed
CN-110691820-B Reinforced polycarbonate resin composition 帝人株式会社 2022-03-18 CN disclosed
CN-114072461-A Thermoplastic resin composition, molded article, and product 三菱电机株式会社 2022-02-18 CN disclosed
WO-2022030410-A1 FILM, WRAPPING ELECTRIC WIRE COATING MATERIAL, FILM FOR FLEXIBLE PRINTED CIRCUIT BOARD, AND LAMINATE ダイキン工業株式会社 2022-02-10 WO disclosed
CN-114026175-A Thermoplastic resin composition 帝人株式会社 2022-02-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287232-A1 BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS HBZ, FHIT, BZW2 APP 4580/4885LMNA 4249/4885NPC1 4749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.