SCHEMBL259532

SCHEMBL259532

C=CC(=O)OCCc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.46
LMNA P02545 3/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
THRB P10828 1/20 0.42
ALOX15 P16050 3/20 0.40
MAPK1 P28482 3/20 0.40
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
CYP3A4 P08684 2/20 0.40
ALOX12 P18054 2/20 0.40
ALOX5 P09917 2/20 0.40
TTR P02766 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
AKR1B10 O60218 1/20 0.40
GMNN O75496 1/20 0.40
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378372 1.00 APP (0.46) APPLMNANPC1RAB9ATHRB
SCHEMBL4195747 0.93 LMNA (0.43) APPLMNANPC1RAB9ATHRB
SCHEMBL29514790 0.93 LMNA (0.43) APPLMNANPC1RAB9ATHRB
SCHEMBL25408635 0.92 LMNA (0.42) APPLMNANPC1RAB9ATHRB
SCHEMBL21836053 0.92 LMNA (0.41) APPLMNANPC1RAB9ATHRB
SCHEMBL29315672 0.91 LMNA (0.41) APPLMNANPC1RAB9ATHRB
SCHEMBL25410461 0.91 LMNA (0.41) APPLMNANPC1RAB9ATHRB
SCHEMBL29437191 0.91 APP (0.41) APPLMNANPC1RAB9ATHRB
SCHEMBL29147588 0.88 LMNA (0.38) APPLMNANPC1RAB9ATHRB
SCHEMBL2777937 0.88 NPC1 (0.47) LMNANPC1RAB9ATHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103426-A Biostable polymer brush with defined viscosity and optical properties for use in novel intraocular lenses 杜克大学 2024-05-28 CN claimed
CN-113574082-A Process for preparing graft polymers 株式会社LG化学 2021-10-29 CN claimed
WO-2021054652-A1 METHOD FOR PREPARING GRAFT POLYMER 주식회사 엘지화학 2021-03-25 WO claimed
EP-1586446-B1 LAMINATE FILM TEIJIN DUPONT FILMS JAPAN LTD (JP) 2010-09-08 EP claimed
US-7264866-B2 Laminate film TEIJIN DUPONT FILMS JAPAN LIMITED (JP) 2007-09-04 US claimed
WO-2006113164-A1 UV-ABSORBING LAYER FOR POLARIZER PLATE NITTO DENKO CORPORATION (JP) 2006-10-26 WO claimed
US-20060234035-A1 Protective cover sheet comprising a UV-absorbing layer for a polarizer plate and method of making the same EASTMAN KODAK COMPANY 2006-10-19 US claimed
US-20060121299-A1 Laminate film TEIJIN DUPONT FILMS JAPAN LIMITED (JP) 2006-06-08 US claimed
EP-1586446-A1 LAMINATE FILM Teijin Dupont Films Japan Limited (JP) 2005-10-19 EP claimed
EP-1543356-A1 METHOD OF MANUFACTURING OPHTHALMIC LENSES MADE FROM HYDROPHOBIC ACRYLIC POLYMERS Medennium, Inc. (US) 2005-06-22 EP claimed
WO-2004029675-A1 METHOD OF MANUFACTURING OPHTHALMIC LENSES MADE FROM HYDROPHOBIC ACRYLIC POLYMERS MEDENNIUM, INC. (US) 2004-04-08 WO claimed
US-20040056371-A1 Method of manufacturing ophthalmic lenses made from hydrophobic acrylic polymers MEDENNIUM, INC. 2004-03-25 US claimed
EP-1078011-B1 UV-STABILIZED AND OTHER MODIFIED POLYCARBONATES AND METHOD OF MAKING SAME GEN ELECTRIC (US) 2002-07-17 EP claimed
EP-1078011-A1 UV-STABILIZED AND OTHER MODIFIED POLYCARBONATES AND METHOD OF MAKING SAME GENERAL ELECTRIC COMPANY (US) 2001-02-28 EP claimed
US-6096852-A MODIFYING ADDITIVE MOLECULE IS GRAFT POLYMERIZED TO THE POLYCARBONATE IN PRESENCE OF A RADICAL POLYMERIZATION INITIATOR GENERAL ELECTRIC COMPANY (US) 2000-08-01 US claimed
WO-1999058593-A1 UV-STABILIZED AND OTHER MODIFIED POLYCARBONATES AND METHOD OF MAKING SAME GENERAL ELECTRIC COMPANY (US) 1999-11-18 WO claimed
EP-4407003-B1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LTD (JP) 2026-04-29 EP disclosed
US-20260098152-A1 RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TEIJIN LIMITED (JP) 2026-04-09 US disclosed
US-5458924-A COATING ARTICLE WITH AN AQUEOUS COPOLYMER EMULSION IPPOSHA OIL INDUSTRIES CO., LTD. (JP) 1995-10-17 US disclosed
EP-0508744-A1 Method of imparting light resistance and ultraviolet-screening action to fibrous article IPPOSHA OIL INDUSTRIES CO. LTD. (JP) 1992-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098152-A1 RESIN COMPOSITION AND MOLDED ARTICLE OF SAME CYC1, MT-CO2, SCO2 APP 1902/4885LMNA 1349/4885NPC1 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.