Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | LMNA | P02545 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SLC25A5 | P05141 | 2/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183977 | 1.00 | MAPT (0.57) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL9403263 | 0.77 | MAPT (0.54) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL30381384 | 0.73 | MAPT (0.63) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL8893921 | 0.68 | MAPT (0.65) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| Anthraquinone SCHEMBL28722909 | 0.66 | MAPT (0.67) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL16769905 | 0.64 | ALDH1A1 (0.72) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL15562489 | 0.64 | ALDH1A1 (0.72) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL15562491 | 0.64 | ALDH1A1 (0.72) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL19462864 | 0.63 | ELANE (0.74) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL9840968 | 0.62 | MAPT (0.41) | MAPTLMNASMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949980-B2 | Drugs to prevent HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | MAPT 4500/4885LMNA 1743/4885SMN1; SMN2 3894/4885 |
| US-20150297602-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | MAPT 4500/4885LMNA 1743/4885SMN1; SMN2 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.