Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HBB | P68871 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SLC25A5 | P05141 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893921 | 0.79 | MAPT (0.65) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL2183971 | 0.77 | MAPT (0.57) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL2183977 | 0.77 | MAPT (0.57) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL9165212 | 0.75 | LMNA (0.44) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL6269114 | 0.71 | NFKB1 (0.42) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL9431982 | 0.71 | MAPT (0.55) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL11451081 | 0.66 | MAPT (1.00) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL115571 | 0.66 | MAPT (0.47) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL2112664 | 0.65 | HBB (0.61) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL29541198 | 0.65 | MAPT (0.57) | MAPTLMNASMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286603-A | Substrate coated with a photopolymerizable compound containing ethylenic unsaturation, a perester photoinitiator and optionally an optical sensitizer | VICKERS PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| US-5130227-A | Multilayer light sensitive plates | VICKERS PLC (GB) | 1992-07-14 | — | — | US | disclosed |
| US-4946960-A | ADDITION POLYMERIZATION CATALYSTS | VICKERS PLC (GB) | 1990-08-07 | — | — | US | disclosed |
| EP-0125140-B1 | IMPROVEMENTS IN OR RELATING TO RADIATION SENSITIVE PLATES | VICKERS PLC (GB) | 1988-12-14 | — | — | EP | disclosed |
| EP-0125875-B1 | IMPROVEMENTS IN OR RELATING TO PERESTER COMPOUNDS | VICKERS PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| EP-0125875-A2 | Improvements in or relating to perester compounds | VICKERS PLC (GB) | 1984-11-21 | — | — | EP | disclosed |