Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | GAA | P10253 | 1/20 | 0.84 |
| ▸ | HPGD | P15428 | 1/20 | 0.84 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | MMP3 | P08254 | 2/20 | 0.57 |
| ▸ | MMP13 | P45452 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | IDH1 | O75874 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17183508 | 1.00 | MAPT (0.84) | MAPTALDH1A1LMNAGAAHPGD | |
| SCHEMBL2184426 | 1.00 | MAPT (0.84) | MAPTALDH1A1LMNAGAAHPGD | |
| SCHEMBL1250835 | 0.82 | CRHBP (0.71) | RAB9AGSK3BCRHBPCRHR2IDH1 | |
| SCHEMBL1250831 | 0.82 | CRHBP (0.71) | RAB9AGSK3BCRHBPCRHR2IDH1 | |
| SCHEMBL15091291 | 0.82 | CRHBP (0.71) | RAB9AGSK3BCRHBPCRHR2IDH1 | |
| SCHEMBL4053689 | 0.78 | CRHBP (0.58) | MAPTALDH1A1LMNAGAAHPGD | |
| SCHEMBL4053687 | 0.78 | CRHBP (0.58) | MAPTALDH1A1LMNAGAAHPGD | |
| SCHEMBL3138641 | 0.77 | MAPT (0.81) | MAPTALDH1A1LMNAGAAHPGD | |
| SCHEMBL3138638 | 0.77 | MAPT (0.81) | MAPTALDH1A1LMNAGAAHPGD | |
| SCHEMBL7969788 | 0.75 | MMP3 (0.67) | GAAHPGDRAB9AMMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066951-B2 | Drugs to treat HPV infection | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165220-A1 | DRUGS TO PREVENT HPV INFECTION | VHL, PHF13, CDKN1A | MAPT 4500/4885ALDH1A1 458/4885LMNA 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.