Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | IDH1 | O75874 | 1/20 | 0.52 |
| ▸ | NAT1 | P18440 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053687 | 1.00 | CRHBP (0.58) | CRHBPCRHR2GSK3BMMP3MMP13 | |
| SCHEMBL1250831 | 0.81 | CRHBP (0.71) | CRHBPCRHR2GSK3BIDH1NAT1 | |
| SCHEMBL1250835 | 0.81 | CRHBP (0.71) | CRHBPCRHR2GSK3BIDH1NAT1 | |
| SCHEMBL15091291 | 0.81 | CRHBP (0.71) | CRHBPCRHR2GSK3BIDH1NAT1 | |
| SCHEMBL7969788 | 0.79 | MMP3 (0.67) | CRHBPCRHR2GSK3BMMP3MMP13 | |
| SCHEMBL7969787 | 0.79 | MMP3 (0.67) | CRHBPCRHR2GSK3BMMP3MMP13 | |
| SCHEMBL2184426 | 0.78 | MAPT (0.84) | CRHBPCRHR2GSK3BMMP3MMP13 | |
| SCHEMBL2184424 | 0.78 | MAPT (0.84) | CRHBPCRHR2GSK3BMMP3MMP13 | |
| SCHEMBL17183508 | 0.78 | MAPT (0.84) | CRHBPCRHR2GSK3BMMP3MMP13 | |
| SCHEMBL13499567 | 0.77 | GAA (0.57) | CRHBPCRHR2GSK3BHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |