SCHEMBL2184430

SCHEMBL2184430

NC(=O)C1NC(=O)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
RGS12 O14924 1/20 0.50
HSD17B10 Q99714 1/20 0.32
BACE1 P56817 1/20 0.32
RBP4 P02753 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.30
APEX1 P27695 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10677331 1.00 TSHR (0.50) TSHRRGS12HSD17B10BACE1RBP4
SCHEMBL3501182 0.80 TSHR (0.44) TSHRRGS12HSD17B10BACE1RBP4
SCHEMBL24132371 0.79 RGS12 (0.37) TSHRRGS12
SCHEMBL16597486 0.79 TSHR (0.44) TSHRRGS12HSD17B10BACE1RBP4
SCHEMBL16597743 0.79 TSHR (0.44) TSHRRGS12HSD17B10BACE1RBP4
Potassium Ion SCHEMBL16597641 0.79 TSHR (0.44) TSHRRGS12HSD17B10BACE1RBP4
SCHEMBL16597493 0.79 TSHR (0.44) TSHRRGS12HSD17B10BACE1RBP4
SCHEMBL2064738 0.78 TSHR (0.42) TSHRRGS12HSD17B10BACE1RBP4
SCHEMBL11628675 0.76 TSHR (0.46) TSHRRGS12HSD17B10BACE1RBP4
SCHEMBL5916254 0.74 TSHR (0.39) TSHRRGS12HSD17B10BACE1RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507150-A Hydantoin precursor liquid and method for preparing glycine by using hydantoin precursor liquid 天宝动物营养科技股份有限公司 2022-05-17 CN claimed
CN-113121375-A Method for preparing food-grade and feed-grade magnesium glycinate and implementation device thereof 铂尊投资集团有限公司 2021-07-16 CN claimed
CN-113105352-A Method for preparing food-grade and feed-grade zinc glycinate and implementation device thereof 铂尊投资集团有限公司 2021-07-13 CN claimed
CN-113105353-A Method for preparing food-grade calcium glycine and co-producing glycine chelated ferrous iron and implementation device thereof 铂尊投资集团有限公司 2021-07-13 CN claimed
CN-113087635-A Comprehensive utilization method of glycine crystallization mother liquor by hydantoin method and implementation device thereof 铂尊投资集团有限公司 2021-07-09 CN claimed
CN-112961063-A Method for preparing glycine metal complex salt and device for implementing same 铂尊投资集团有限公司 2021-06-15 CN claimed
CN-111635331-A Method for preparing glycine chelate and microelement fertilizer/efficient slow-release fertilizer by using glycine mother liquor 天宝动物营养科技股份有限公司 2020-09-08 CN claimed
CN-1260956-A Broad-spectrum bactericide mixed preparation for preventing and treating soil-borne diseases INST PLANT PROTECTION IPP CAAS (CN) 2000-07-26 CN claimed
US-4776879-A Water insoluble triazone fertilizer and methods of making and use TRIAZONE CORPORATION (US) 1988-10-11 US claimed
JP-57122007-A None JP disclosed
US-12187669-B2 Method for producing methionine EVONIK OPERATIONS GMBH (DE) 2025-01-07 US disclosed
EP-4058448-B1 HYDANTOIN DERIVATIVES AS ADAMTS7 ANTAGONISTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES BAYER AG (DE) 2024-05-29 EP disclosed
CN-113166045-B Method for producing methionine 赢创运营有限公司 2024-03-08 CN disclosed
CN-110088085-B Method for producing methionine 赢创运营有限公司 2024-01-19 CN disclosed
WO-1999003345-A1 EFFECT ENHANCER FOR AGRICULTURAL CHEMICAL KAO CORPORATION (JP) 1999-01-28 WO disclosed
EP-0290102-A2 Water-insoluble triazone fertilizer and method of making and use TRIAZONE CORPORATION (US) 1988-11-09 EP disclosed
JP-S57122007-A FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL PURPOSE HOKKO CHEM IND CO LTD 1982-07-29 JP disclosed
US-4281140-A REACTING AN ISOCYANATE OR ISOTHIOCYANATE WITH AN UNSATURATED DIAMINE BAYER AKTIENGESELLSCHAFT (DE) 1981-07-28 US disclosed
US-4182812-A FROM POLYISOCYANATES OR POLYISOTHIOCYANATES AND AN UNSATURATED DIAMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-01-08 US disclosed
US-4170701-A Process for the preparation of (thio)hydantoins modified with amide groups BAYER AKTIENGESELLSCHAFT (DE) 1979-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12187669-B2 Method for producing methionine MGMT, MB, BHMT2 TSHR 2629/4885RGS12 4310/4885HSD17B10 169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.