Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.43 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24763632 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1HPGDALDH1A1RAB9A | |
| SCHEMBL11242352 | 0.95 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1HPGDALDH1A1RAB9A | |
| SCHEMBL14097842 | 0.82 | ESR1 (0.43) | SMN1; SMN2RAB9ANPC1L3MBTL1TNK2 | |
| SCHEMBL15371049 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2HPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL1129701 | 0.82 | KMT2A (0.56) | SMN1; SMN2HPGDALDH1A1NPC1TNK2 | |
| SCHEMBL28263198 | 0.81 | SLC6A2 (0.46) | SMN1; SMN2HPGDALDH1A1RAB9ALMNA | |
| SCHEMBL9336828 | 0.81 | HPGD (0.50) | SMN1; SMN2HPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL11249479 | 0.80 | SLC6A2 (0.45) | SMN1; SMN2HPGDALDH1A1RAB9ALMNA | |
| SCHEMBL29307998 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1HPGDALDH1A1RAB9A | |
| SCHEMBL8024954 | 0.77 | KMT2A (0.48) | HPGDALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342200-A2 | COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010036630-A2 | COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |