SCHEMBL2184728

SCHEMBL2184728

C=C(C)C(=O)OCC(O)COc1ccc(C(C)(C)C)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
LMNA P02545 3/20 0.50
POLB P06746 3/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HSD17B10 Q99714 1/20 0.49
GAA P10253 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
ALDH1A1 P00352 2/20 0.47
USP2 O75604 1/20 0.47
HTT P42858 3/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP1A2 P05177 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HIF1A Q16665 1/20 0.44
AR P10275 1/20 0.43
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13792062 0.92 POLB (0.50) MAPTLMNAPOLBNPSR1HSD17B10
SCHEMBL22020008 0.92 HTT (0.53) MAPTLMNAPOLBNPSR1HSD17B10
SCHEMBL20610370 0.92 HTT (0.53) MAPTLMNAPOLBNPSR1HSD17B10
SCHEMBL14173202 0.92 HTT (0.53) MAPTLMNAPOLBNPSR1HSD17B10
SCHEMBL11967041 0.92 HTT (0.53) MAPTLMNAPOLBNPSR1HSD17B10
SCHEMBL15349 0.92 HTT (0.53) MAPTLMNAPOLBNPSR1HSD17B10
Bicarbonate SCHEMBL7732697 0.90 HTT (0.51) MAPTLMNAPOLBNPSR1HSD17B10
SCHEMBL19479960 0.88 AR (0.54) MAPTLMNAPOLBNPSR1HSD17B10
Methacrylic Acid SCHEMBL14881206 0.88 HTT (0.50) MAPTLMNAPOLBNPSR1SMN1; SMN2
SCHEMBL15803522 0.88 HTT (0.50) MAPTLMNAPOLBNPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0130680-A2 Cure to elastomers composition LOCTITE CORPORATION (US) 1985-01-09 EP claimed
US-4439600-A Cure to elastomers compositions LOCTITE CORPORATION (US) 1984-03-27 US claimed
EP-2346910-B1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI DENTAL DIVISION (US) 2016-07-13 EP disclosed
EP-2346910-B1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI DENTAL DIVISION (US) 2016-07-13 EP disclosed
US-8906981-B2 Dental compositions comprising semi-crystalline resin and nanocluster filler 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-09 US disclosed
US-8906981-B2 Dental compositions comprising semi-crystalline resin and nanocluster filler 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-09 US disclosed
US-8513326-B2 Carbamate-methacrylate monomers and their use in dental applications SEPTODONT CONFI-DENTAL (US) 2013-08-20 US disclosed
US-8513326-B2 Carbamate-methacrylate monomers and their use in dental applications SEPTODONT CONFI-DENTAL (US) 2013-08-20 US disclosed
US-8513326-B2 Carbamate-methacrylate monomers and their use in dental applications SEPTODONT CONFI-DENTAL (US) 2013-08-20 US disclosed
CN-102405241-A Carbamate-methylpropionate monomers and their use in dental applications SEPTODONT CONFI DENTAL DIVISIO 2012-04-04 CN disclosed
EP-2346910-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS Septodont Confi-Dental Division (US) 2011-07-27 EP disclosed
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-12-09 US disclosed
WO-2010042818-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-04-15 WO disclosed
WO-2010042818-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-04-15 WO disclosed
EP-1213619-A1 Method for preparing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-06-12 EP disclosed
US-4923905-A DIKETONE AND POLYPEROXY ESTER OF BENZOPHENONE POLYMERIZATION INITIATOR NIPPON OIL AND FATS CO., LTD. (JP) 1990-05-08 US disclosed
EP-0176777-B1 LIGHT CURABLE DENTAL COMPOSITION NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-11-23 EP disclosed
US-4824876-A ORGANIC PEROXIDE, PYRYLIUM SALT INIATOR NIPPON OIL AND FATS CO., LTD. (JP) 1989-04-25 US disclosed
US-4746685-A METHACRYLATE COMPOUND WITH AN ORGANIC PEROXIDE AND PYRYCIUM SALT AS A LIGHT POLYMERIZATION NIPPON OIL AND FATS CO., LTD. (JP) 1988-05-24 US disclosed
EP-0176777-A2 Light curable dental composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1986-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS CAD, ACMSD, MMAB MAPT 775/4885LMNA 1883/4885POLB 2038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.