SCHEMBL21847490

SCHEMBL21847490

CC1=CC(C)(N)CC(C)=C1c1ccc(N)cc1.c1ccc(Pc2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9224983 0.83 KDM1A (0.32)
SCHEMBL24245352 0.74 CYP3A4 (0.34) CYP3A4TAAR1HSD17B10TDP1
SCHEMBL9618210 0.65 TSHR (0.53) CYP3A4TAAR1HSD17B10TDP1
SCHEMBL21847487 0.65 MAOA (0.32)
Water SCHEMBL27261489 0.63 TSHR (0.50) CYP3A4TAAR1HSD17B10TDP1
Aniline SCHEMBL28159853 0.63 TSHR (0.65) CYP3A4TAAR1HSD17B10TDP1
SCHEMBL21242653 0.59 NPC1 (0.43)
Methylamine SCHEMBL28276546 0.59 TSHR (0.37) CYP3A4TDP1
SCHEMBL20860342 0.57 CYP3A4 (0.37) CYP3A4TAAR1HSD17B10TDP1
SCHEMBL21538257 0.57 MMP3 (0.48) CYP3A4TAAR1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3638725-A1 ADDITIVE MANUFACTURING PROCESS USING AMINES FOR THE POST-HARDENING Covestro Deutschland AG (DE) 2020-04-22 EP disclosed