SCHEMBL24245352

SCHEMBL24245352

CC1=CC(C)(C)CC(C)=C1c1ccc(N)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
ACHE P22303 1/20 0.32
CYP19A1 P11511 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3679612 0.81 PGR (0.33) ALDH1A1
SCHEMBL21847490 0.74 CYP3A4 (0.33) CYP3A4TDP1TAAR1HSD17B10
SCHEMBL20860342 0.70 CYP3A4 (0.37) CYP3A4TDP1ALDH1A1TP53ACHE
SCHEMBL19265041 0.70
SCHEMBL31281526 0.65
SCHEMBL23938640 0.64 CYP3A4 (0.34) CYP3A4TDP1ALDH1A1TP53ACHE
SCHEMBL17710637 0.62
SCHEMBL31281817 0.60
SCHEMBL21180875 0.59
Benzidine SCHEMBL27459735 0.58 ALDH1A1 (0.85) CYP3A4TDP1ALDH1A1TP53ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604321-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2022-02-09 EP disclosed