Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185728 | 0.87 | BACE1 (0.34) | CHRNB2CHRNA4NR1H2 | |
| SCHEMBL3358712 | 0.76 | AKT1 (0.38) | NR1H2 | |
| SCHEMBL2184837 | 0.76 | CHRNB2 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL2300520 | 0.75 | DGAT1 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL2185911 | 0.75 | DGAT1 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL2185542 | 0.73 | AKT1 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL2184886 | 0.73 | SLC5A1 (0.31) | — | |
| SCHEMBL2307750 | 0.73 | AKT1 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL2185799 | 0.71 | CHRNB2 (0.61) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3356520 | 0.71 | CHRNB2 (0.62) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342192-A2 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | Psychogenics Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010045212-A2 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | PSYCHOGENICS, INCSTATUTS (US) | 2010-04-22 | — | — | WO | disclosed |