Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185728 | 0.85 | BACE1 (0.34) | SLC5A1 | |
| SCHEMBL3358712 | 0.81 | AKT1 (0.38) | SLC5A1 | |
| SCHEMBL2184888 | 0.80 | CHRNB1 (0.40) | — | |
| SCHEMBL2307750 | 0.76 | AKT1 (0.38) | — | |
| SCHEMBL2184835 | 0.73 | CHRNB2 (0.33) | — | |
| SCHEMBL2185542 | 0.72 | AKT1 (0.36) | SLC5A1 | |
| SCHEMBL2186288 | 0.70 | CYP4F2 (0.40) | SLC5A1 | |
| SCHEMBL2300520 | 0.69 | DGAT1 (0.37) | — | |
| SCHEMBL2185911 | 0.69 | DGAT1 (0.37) | — | |
| SCHEMBL2185877 | 0.68 | CFD (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342192-A2 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | Psychogenics Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010045212-A2 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | PSYCHOGENICS, INCSTATUTS (US) | 2010-04-22 | — | — | WO | disclosed |