SCHEMBL2184872

SCHEMBL2184872

C=C(C)C(=O)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.46
HPGD P15428 1/20 0.40
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MAPT P10636 3/20 0.37
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
ATM Q13315 2/20 0.33
TSHR P16473 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
PAX8 Q06710 1/20 0.33
LMNA P02545 1/20 0.33
XBP1 P17861 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28422623 0.85 LMNA (0.37) ALDH1A1CES2CES1MAPTTDP1
SCHEMBL28890772 0.84 ELANE (0.46) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL1943281 0.84 ELANE (0.46) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL1719096 0.82 ELANE (0.45) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL21382642 0.82 ALDH1A1 (0.32) ELANEHPGDALDH1A1MAPTLMNA
SCHEMBL8356581 0.82 ELANE (0.45) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL6884399 0.82 LMNA (0.39) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL9411498 0.82 ELANE (0.45) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL3294124 0.81 ELANE (0.39) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL3297934 0.81 ELANE (0.39) ELANEHPGDALDH1A1KDM4ECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001345-B1 DEGRADABLE HYPERBRANCHED RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF UNIV SOUTH CHINA TECH (CN) 2026-04-01 EP claimed
EP-4001345-A1 DEGRADABLE HYPERBRANCHED RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF South China University of Technology (CN) 2022-05-25 EP claimed
CN-110511328-B Branched-point-breaking type hyperbranched resin and preparation method and application thereof 华南理工大学 2020-11-24 CN claimed
CN-110540652-B Degradable hyperbranched resin and preparation method and application thereof 华南理工大学 2020-07-28 CN claimed
CN-110540652-A degradable hyperbranched resin and preparation method and application thereof UNIV SOUTH CHINA TECH 2019-12-06 CN claimed
CN-108727545-A A kind of anticorrosion and antifouling type coating resin and preparation method thereof 鲁东大学 2018-11-02 CN claimed
CN-107868182-A A kind of polynary collaboration antifouling paint resin and preparation method thereof 天津大学 2018-04-03 CN claimed
US-9701794-B2 Method for preparing main chain scission-type polysilyl (meth)acrylate resin and application thereof SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2017-07-11 US claimed
US-20160185913-A1 METHOD FOR PREPARING MAIN CHAIN SCISSION-TYPE POLYSILYL (METH)ACRYLATE RESIN AND APPLICATION THEREOF SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2016-06-30 US claimed
CN-103396513-B A kind of preparation method of main chain fracture type polyacrylic acid silane ester resin and application SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2016-03-02 CN claimed
US-7297727-B2 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. (US) 2007-11-20 US claimed
US-20060252953-A1 Process for the production of silyl carboxylate monomers SIGMA COATINGS B.V. (NL) 2006-11-09 US claimed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP claimed
EP-1572702-A1 PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2005-09-14 EP claimed
EP-1479737-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions Atofina Chemicals, Inc. (US) 2004-11-24 EP claimed
US-20040138332-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2004-07-15 US claimed
WO-2004056838-A1 PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2004-07-08 WO claimed
EP-1431301-A1 Process for the production of silyl carboxylate monomers SIGMA COATINGS B.V. (NL) 2004-06-23 EP claimed
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 US claimed
EP-1367100-A1 Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions ATOFINA CHEMICALS, INC. (US) 2003-12-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252953-A1 Process for the production of silyl carboxylate monomers ACSL1, SUCLA2, MSMO1 ELANE 2684/4885HPGD 417/4885ALDH1A1 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.