SCHEMBL28890772

SCHEMBL28890772

C=C(C)C(=O)O[Si](OC(=O)C(=C)C)(OC(=O)C(=C)C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.46
HPGD P15428 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MAPT P10636 3/20 0.37
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
ATM Q13315 3/20 0.33
TSHR P16473 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
PAX8 Q06710 1/20 0.33
LMNA P02545 1/20 0.33
XBP1 P17861 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2579122 0.91 ELANE (0.42) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL2578321 0.86 ALDH1A1 (0.41) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL2184872 0.84 ELANE (0.46) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL1943281 0.84 ELANE (0.46) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL28890782 0.82 LMNA (0.39) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL9411498 0.82 ELANE (0.45) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL8356581 0.82 ELANE (0.45) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL1719096 0.82 ELANE (0.45) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL132933 0.81 CES2 (0.43) ELANEHPGDALDH1A1KDM4ECES2
SCHEMBL679391 0.81 PAX8 (0.36) ELANEHPGDALDH1A1KDM4ECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106605309-B LED lamp, manufacturing method of LED lamp and sealing method of LED device 英克伦股份有限公司 2022-10-18 CN disclosed