SCHEMBL21850146

SCHEMBL21850146

C#CCCC(CCC#N)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 2/20 0.41
CES1 P23141 3/20 0.38
KMT2A Q03164 6/20 0.36
MEN1 O00255 4/20 0.36
CYP3A4 P08684 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALDH1A1 P00352 5/20 0.34
MAPT P10636 5/20 0.34
HPGD P15428 2/20 0.34
CTNNB1 P35222 1/20 0.33
ALOX15 P16050 2/20 0.33
GUSB P08236 1/20 0.33
USP2 O75604 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SRC P12931 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22047370 0.92 MLYCD (0.46) MLYCDCES1KMT2AMEN1CYP3A4
SCHEMBL11620954 0.78 MLYCD (0.46) MLYCDCES1KMT2AMEN1CYP3A4
SCHEMBL11245491 0.77 MLYCD (0.44) MLYCDCES1KMT2AMEN1CYP3A4
SCHEMBL29256384 0.74 MLYCD (0.43) MLYCDCES1KMT2AMEN1CYP3A4
SCHEMBL21850134 0.70 CTSS (0.40) MLYCDCES1ALDH1A1MAPTMAPK1
Methoxymethane SCHEMBL11307133 0.70 CES1 (0.47) MLYCDCES1KMT2AMEN1CYP3A4
SCHEMBL10944183 0.70 MLYCD (0.42) MLYCDKMT2AMEN1ALDH1A1MAPT
SCHEMBL21850140 0.68 KMT2A (0.49) MLYCDKMT2AMEN1CYP3A4CYP1A2
SCHEMBL28371700 0.68 MAPT (0.38) MLYCDCES1KMT2AALDH1A1MAPT
Ether SCHEMBL11315900 0.67 ALDH1A1 (0.41) MLYCDCES1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3629411-A1 ELECTROLYTE AND BATTERY Contemporary Amperex Technology Co., Limited (CN) 2020-04-01 EP disclosed