Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21850201 | 0.74 | MAPT (0.32) | MAPT | |
| Nitric Acid SCHEMBL10641276 | 0.67 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTLMNAHTT | |
| SCHEMBL21850231 | 0.65 | MAPT (0.31) | MAPT | |
| SCHEMBL20460999 | 0.65 | ADH1B (0.35) | — | |
| SCHEMBL20461064 | 0.64 | — | — | |
| SCHEMBL20053920 | 0.64 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL22060817 | 0.64 | — | — | |
| SCHEMBL2337763 | 0.63 | KMT2A (0.39) | ALDH1A1GAAMAPTLMNAHTT | |
| SCHEMBL295996 | 0.63 | LMNA (0.41) | ALDH1A1GAAMAPTLMNAHTT | |
| SCHEMBL22061464 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099695-B1 | COMPOUNDS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-04-08 | — | — | EP | disclosed |