Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.45 |
| ▸ | FLT3 | P36888 | 5/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.45 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26944787 | 0.88 | CSF1R (0.44) | CSF1RPDGFRAFLT3PDGFRBKIT | |
| SCHEMBL26944181 | 0.87 | CSF1R (0.48) | CSF1RPDGFRAFLT3PDGFRBKIT | |
| SCHEMBL26944854 | 0.87 | CSF1R (0.45) | CSF1RPDGFRAFLT3PDGFRBKIT | |
| SCHEMBL26944765 | 0.84 | CSF1R (0.42) | CSF1RPDGFRAFLT3PDGFRBKIT | |
| SCHEMBL21824020 | 0.78 | CSF1R (0.68) | CSF1RPDGFRAFLT3PDGFRBKIT | |
| SCHEMBL21425632 | 0.75 | TGFBR1 (0.46) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL21823990 | 0.74 | CSF1R (0.54) | CSF1RPDGFRAFLT3PDGFRBKIT | |
| SCHEMBL21824034 | 0.74 | CSF1R (0.69) | CSF1RPDGFRAFLT3PDGFRBKIT | |
| SCHEMBL26944852 | 0.73 | CSF1R (0.54) | CSF1RPDGFRAFLT3PDGFRBKIT | |
| SCHEMBL21851749 | 0.72 | TGFBR1 (0.36) | CSF1RPDGFRAFLT3PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632906-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |