Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 7/20 | 0.36 |
| ▸ | CSF1R | P07333 | 5/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.34 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | PYGM | P11217 | 1/20 | 0.31 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21425632 | 0.87 | TGFBR1 (0.46) | TGFBR1CSF1RKDRPDGFRBPDGFRA | |
| SCHEMBL21882310 | 0.75 | CSF1R (0.34) | TGFBR1CSF1RKDRPDGFRBPDGFRA | |
| SCHEMBL21425572 | 0.73 | CSF1R (0.35) | TGFBR1CSF1RKDRPDGFRBPDGFRA | |
| SCHEMBL21882349 | 0.73 | TGFBR1 (0.38) | TGFBR1CSF1RPDGFRBPDGFRA | |
| SCHEMBL21882307 | 0.71 | CSF1R (0.32) | TGFBR1CSF1RPDGFRBPDGFRA | |
| SCHEMBL21882296 | 0.71 | CSF1R (0.34) | TGFBR1CSF1RKDRPDGFRBPDGFRA | |
| SCHEMBL26944690 | 0.71 | CSF1R (0.37) | TGFBR1CSF1RKDRPDGFRBPDGFRA | |
| SCHEMBL26944765 | 0.71 | CSF1R (0.42) | CSF1RKDRPDGFRBPDGFRAFLT3 | |
| SCHEMBL27116653 | 0.70 | CSF1R (0.40) | TGFBR1CSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL26944748 | 0.70 | CSF1R (0.35) | CSF1RKDRPDGFRBPDGFRAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632906-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |