Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 5/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 2/20 | 0.37 |
| ▸ | CD99 | P14209 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010368 | 1.00 | CDA (0.43) | CDAMAPTOGASLC5A2PDE2A | |
| SCHEMBL6927896 | 0.84 | MAPT (0.50) | CDAMAPTSLC5A2PYGL | |
| SCHEMBL7199367 | 0.84 | MAPT (0.50) | CDAMAPTSLC5A2PYGL | |
| SCHEMBL6784675 | 0.84 | MAPT (0.50) | CDAMAPTSLC5A2PYGL | |
| SCHEMBL8722212 | 0.84 | MAPT (0.50) | CDAMAPTSLC5A2PYGL | |
| SCHEMBL1525779 | 0.84 | MAPT (0.50) | CDAMAPTSLC5A2PYGL | |
| SCHEMBL6785146 | 0.84 | MAPT (0.50) | CDAMAPTSLC5A2PYGL | |
| SCHEMBL6421045 | 0.84 | MAPT (0.50) | CDAMAPTSLC5A2PYGL | |
| SCHEMBL4666736 | 0.84 | MAPT (0.50) | CDAMAPTSLC5A2PYGL | |
| SCHEMBL25608169 | 0.74 | SLC5A2 (0.53) | SLC5A2PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102199181-B | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | GILEAD PHARMASSET LLC | 2014-09-17 | — | — | CN | disclosed |
| US-8481713-B2 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | GILEAD PHARMASSET LLC (US) | 2013-07-09 | — | — | US | disclosed |
| CN-102199181-A | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSET INC | 2011-09-28 | — | — | CN | disclosed |
| EP-2348029-A1 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives | Pharmasset, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |
| CN-101023094-B | Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSET LTD | 2011-05-18 | — | — | CN | disclosed |
| US-7601820-B2 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSET, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| CN-101023094-A | Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSET INC (US) | 2007-08-22 | — | — | CN | disclosed |
| US-20060199783-A1 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSETT, INC. (US) | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199783-A1 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | NSUN2, FBL, UMPS | CDA 30/4885MAPT 4801/4885OGA 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.