Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CDA | P32320 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 3/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666736 | 1.00 | MAPT (0.50) | MAPTCDAPYGLSLC5A2HIF1A | |
| SCHEMBL6785146 | 1.00 | MAPT (0.50) | MAPTCDAPYGLSLC5A2HIF1A | |
| SCHEMBL7199367 | 1.00 | MAPT (0.50) | MAPTCDAPYGLSLC5A2HIF1A | |
| SCHEMBL8722212 | 1.00 | MAPT (0.50) | MAPTCDAPYGLSLC5A2HIF1A | |
| SCHEMBL1525779 | 1.00 | MAPT (0.50) | MAPTCDAPYGLSLC5A2HIF1A | |
| SCHEMBL6784675 | 1.00 | MAPT (0.50) | MAPTCDAPYGLSLC5A2HIF1A | |
| SCHEMBL6927896 | 1.00 | MAPT (0.50) | MAPTCDAPYGLSLC5A2HIF1A | |
| SCHEMBL28147525 | 0.85 | HIF1A (0.45) | MAPTCDAPYGLSLC5A2HIF1A | |
| SCHEMBL2185181 | 0.84 | CDA (0.43) | MAPTCDAPYGLSLC5A2 | |
| SCHEMBL5010368 | 0.84 | CDA (0.43) | MAPTCDAPYGLSLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2851094-B2 | — | — | 1999-01-27 | — | — | JP | claimed |
| EP-0357571-B1 | Pyrimidine nucleosides | MEDIVIR AB (SE) | 1996-04-03 | — | — | EP | claimed |
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | claimed |
| WO-1989012061-A1 | PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES | MEDIVIR AB (SE) | 1989-12-14 | — | — | WO | claimed |
| US-6867199-B2 | Dinucleoside polyphosphate compositions and their therapeutic use | INSPIRE PHARMACEUTICALS, INC. (US) | 2005-03-15 | — | — | US | disclosed |
| US-20030207825-A1 | Dinucleoside polyphosphate compositions and their therapeutic use | Outdoor Wireless Networks LLC | 2003-11-06 | — | — | US | disclosed |
| US-6555675-B2 | Dinucleoside polyphosphates which facilitate secretory mechanisms, i.e. increasing the hydration of mucus secretions, stimulating the production of mucins and increasing ciliary beat frequency to facilitate clearance | INSPIRE PHARMACEUTICALS, INC. | 2003-04-29 | — | — | US | disclosed |
| US-20020103158-A1 | Dinucleoside polyphosphate compositions and their therapeutic use as purinergic receptor agonists | INSPIRE PHARMACEUTICALS, INC. | 2002-08-01 | — | — | US | disclosed |
| US-6331287-B1 | NONCATABOLIZING IMAGING AGENT FOR POSITRON EMISSION TOMOGRAPHY; | UNIVERSITY ADVANCED BIO-IMAGING ASSOCIATES | 2001-12-18 | — | — | US | disclosed |
| WO-1999044646-A1 | NOVEL IMAGING AGENTS AND METHODS FOR THE PREPARATION AND USE THEREOF | UNIVERSITY ADVANCED BIO-IMAGING ASSOCIATES (US) | 1999-09-10 | — | — | WO | disclosed |
| US-5879661-A | Imaging agents and methods for the preparation and use thereof | UNIVERSITY ADVANCED BIO-IMAGING ASSOCIATES (US) | 1999-03-09 | — | — | US | disclosed |
| WO-1997007829-A1 | NOVEL IMAGING AGENTS AND METHODS FOR THE PREPARATION AND USE THEREOF | UNIVERSITY ADVANCED BIO-IMAGING ASSOCIATES (US) | 1997-03-06 | — | — | WO | disclosed |
| US-5246924-A | Method for treating hepatitis B virus infections using 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0338042-A4 | COMPOSITION AND METHOD FOR TREATING HEPATITIS VIRUS INFECTIONS USING 1-(2'-DEOXY-2'-FLUORO-BETA-D-ARABINOFURANOSYL)-5-ETHYLURACIL | — | 1990-09-26 | — | — | EP | disclosed |
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | disclosed |
| WO-1989012061-A1 | PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES | MEDIVIR AB (SE) | 1989-12-14 | — | — | WO | disclosed |
| EP-0338042-A1 | COMPOSITION AND METHOD FOR TREATING HEPATITIS VIRUS INFECTIONS USING 1-(2'-DEOXY-2'-FLUORO-BETA-D-ARABINOFURANOSYL)-5-ETHYLURACIL | Sloan-Kettering Institute For Cancer Research (US) | 1989-10-25 | — | — | EP | disclosed |
| EP-0322384-A1 | Nucleosides for use in therapy | Medivir Aktiebolag (SE) | 1989-06-28 | — | — | EP | disclosed |
| WO-1989001776-A1 | COMPOSITION AND METHOD FOR TREATING HEPATITIS VIRUS INFECTIONS USING 1-(2'-DEOXY-2'-FLUORO-BETA-D-ARABINOFURANOSYL)-5-ETHYLURACIL | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1989-03-09 | — | — | WO | disclosed |
| US-3856777-A | METHOD OF PRODUCING PYRIMIDINE NUCLEOSIDE DERIVATIVES | AJINOMOTO KK | 1974-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103158-A1 | Dinucleoside polyphosphate compositions and their therapeutic use as purinergic receptor agonists | P2RY1, P2RY10, P2RX3 | MAPT 4776/4885CDA 304/4885PYGL 1143/4885 |
| US-20030207825-A1 | Dinucleoside polyphosphate compositions and their therapeutic use | P2RY1, P2RY10, P2RY11 | MAPT 4832/4885CDA 1388/4885PYGL 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.