SCHEMBL2185204

SCHEMBL2185204

O=C(O)CCCSCCNCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
LMNA P02545 3/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PTGS1 P23219 1/20 0.42
BHMT Q93088 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.40
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
PRMT1 Q99873 1/20 0.38
ALDH1A1 P00352 1/20 0.37
CAMK2A Q9UQM7 1/20 0.36
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7719757 0.94 BHMT (0.49) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL7721748 0.87 LMNA (0.64) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL756105 0.82 TSHR (0.71) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL31241576 0.79 TSHR (0.68) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL1251621 0.79 LMNA (0.41) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL7721691 0.78 CYP2D6 (0.48) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL6866613 0.77 LMNA (0.78) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL288365 0.77 LMNA (0.53) TSHRLMNAKMT2ASLC22A6NFKB1
SCHEMBL7720625 0.77 CYP2D6 (0.46) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL5566705 0.77 TSHR (0.54) TSHRLMNAKMT2AHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110177004-A1 Version of FDG Detectable by Single-Photon Emission Computed Tomography OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.) 2011-07-21 US claimed
US-6395930-B1 AMINE SULFIDE PHOSPHATE OR SULFATE REAGENTS WARNER LAMBERT 2002-05-28 US claimed
US-20230143949-A1 MICROBEADS AND USES THEREOF SHANGHAI POLARIS BIOLOGY CO., LTD. (CN) 2023-05-11 US disclosed
EP-4154000-A1 MICROBEADS AND USES THEREOF Shanghai Polaris Biology Co., Ltd. (CN) 2023-03-29 EP disclosed
CN-115667926-A Microbeads and use thereof 上海宸安生物科技有限公司 2023-01-31 CN disclosed
WO-2021233303-A1 MICROBEADS AND USES THEREOF SHANGHAI POLARIS BIOLOGY CO., LTD. (CN) 2021-11-25 WO disclosed
US-9217009-B2 Version of FDG detectable by single-photon emission computed tomography MALLINCKRODT LLC (US) 2015-12-22 US disclosed
US-20140378677-A1 VERSION OF FDG DETECTABLE BY SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY MALLINCKRODT VETERINARY, INC. 2014-12-25 US disclosed
US-8858916-B2 Metal chelate linked to a hexose carrier for use as a metallopharmaceutical diagnostic or therapeutic agent MALLINCKRODT LLC (US) 2014-10-14 US disclosed
US-20110177004-A1 Version of FDG Detectable by Single-Photon Emission Computed Tomography OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.) 2011-07-21 US disclosed
EP-2341944-A2 CONJUGATES OF HEXOSE AND METAL COORDINATING COMPOUNDS FOR IMAGING PURPOSES Mallinckrodt Inc. (US) 2011-07-13 EP disclosed
EP-0971747-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 2000-01-19 EP disclosed
EP-0946202-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1999-10-06 EP disclosed
WO-1998052609-A1 SONODYNAMIC THERAPY USING AN ULTRASOUND SENSITIZER COMPOUND NYCOMED IMAGING AS (NO) 1998-11-26 WO disclosed
WO-1998048838-A1 COMPOUNDS NYCOMED IMAGING AS (NO) 1998-11-05 WO disclosed
WO-1998047541-A1 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1998-10-29 WO disclosed
US-5817774-A Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods STERLING WINTHROP INCORPORATION (US) 1998-10-06 US disclosed
WO-1998018496-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1998-05-07 WO disclosed
WO-1998018497-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1998-05-07 WO disclosed
US-5559214-A Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods STERLING WINTHROP INC. (US) 1996-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177004-A1 Version of FDG Detectable by Single-Photon Emission Computed Tomography SLC2A1, SLC2A4, SLC2A3 TSHR 2360/4885LMNA 4406/4885KMT2A 2498/4885
US-20140378677-A1 VERSION OF FDG DETECTABLE BY SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY SLC2A1, SLC2A4, SLC2A3 TSHR 2360/4885LMNA 4406/4885KMT2A 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.