SCHEMBL2185228

SCHEMBL2185228

COc1ccc(N)cc1-c1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AGPAT2 O15120 8/20 0.49
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 4/20 0.45
NTRK1 P04629 1/20 0.44
USP2 O75604 1/20 0.43
RECQL P46063 1/20 0.42
ERN1 O75460 1/20 0.42
MAPT P10636 3/20 0.42
GAA P10253 2/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2785782 0.89 ALDH1A1 (0.53) AGPAT2KDM4EALDH1A1NTRK1RECQL
SCHEMBL3784958 0.89 NTRK1 (0.49) KDM4EALDH1A1NTRK1USP2MAPT
SCHEMBL7632963 0.86 IMPDH2 (0.46) AGPAT2KDM4EALDH1A1NTRK1USP2
SCHEMBL5841896 0.84 TDP1 (0.54) KDM4EALDH1A1NTRK1USP2MAPT
SCHEMBL23525668 0.83 ERN1 (0.48) KDM4EALDH1A1NTRK1USP2ERN1
SCHEMBL5843621 0.82 FYN (0.46) KDM4EALDH1A1NTRK1USP2ERN1
SCHEMBL654302 0.81 PTGDR2 (0.57) KDM4EALDH1A1NTRK1USP2MAPT
SCHEMBL12493625 0.81 AGPAT2 (0.52) AGPAT2KDM4EALDH1A1MAPTGAA
SCHEMBL3841461 0.81 PDE4D (0.52) AGPAT2KDM4EALDH1A1MAPTTSHR
SCHEMBL27185972 0.80 ALDH1A1 (0.55) KDM4EALDH1A1USP2MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2683682-A1 PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE BASF SE (DE) 2014-01-15 EP disclosed
EP-2342174-B1 METHOD FOR PRODUCING 3-AMINOBIPHENYLENE UNIV MUENCHEN TECH (DE) 2013-03-27 EP disclosed
EP-2342174-B1 METHOD FOR PRODUCING 3-AMINOBIPHENYLENE UNIV MUENCHEN TECH (DE) 2013-03-27 EP disclosed
EP-2546229-A1 Method for synthesising aminobiphenyls Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2013-01-16 EP disclosed
EP-2546229-A1 Method for synthesising aminobiphenyls Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2013-01-16 EP disclosed
WO-2012120003-A1 PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2012-09-13 WO disclosed
WO-2012120003-A1 PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2012-09-13 WO disclosed
EP-2342174-A1 METHOD FOR PRODUCING 3-AMINOBIPHENYLENE Technische Universität München (DE) 2011-07-13 EP disclosed
WO-2010037531-A1 METHOD FOR PRODUCING 3-AMINOBIPHENYLENE Technische Universität München (DE) 2010-04-08 WO disclosed
WO-2010037531-A1 METHOD FOR PRODUCING 3-AMINOBIPHENYLENE Technische Universität München (DE) 2010-04-08 WO disclosed