Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 3/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608022 | 0.93 | BBOX1 (0.45) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL22616415 | 0.90 | BBOX1 (0.48) | BBOX1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL29206222 | 0.86 | BBOX1 (0.40) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL11879870 | 0.82 | SLC22A1 (0.48) | ALDH1A1TP53TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL9785032 | 0.81 | SLC22A1 (0.46) | BBOX1ALDH1A1TP53TSHRSMN1; SMN2 | |
| Tetrabuthylammonium SCHEMBL8846092 | 0.79 | SLC22A1 (0.46) | BBOX1ALDH1A1LMNATP53TSHR | |
| SCHEMBL11244311 | 0.79 | APP (0.42) | LMNABLM | |
| SCHEMBL16211685 | 0.78 | BBOX1 (0.64) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL16736475 | 0.74 | BBOX1 (0.65) | BBOX1GMNNALDH1A1LMNATP53 | |
| Sulfuric Acid SCHEMBL4411418 | 0.74 | SLC22A1 (0.54) | ALDH1A1TP53TSHRSMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304604-A1 | ORGANOSILANES FOR THE TREATMENT OF INFECTIONS | TOPIKOS SCIENTIFIC, INC. (US) | 2025-10-02 | — | — | US | disclosed |
| US-12180239-B2 | Organosilanes for the treatment of infections | TOPIKOS SCIENTIFIC, INC. (US) | 2024-12-31 | — | — | US | disclosed |
| US-20210253607-A1 | ORGANOSILANES FOR THE TREATMENT OF INFECTIONS | TOPIKOS PHARMACEUTICALS, INC. (US) | 2021-08-19 | — | — | US | disclosed |
| WO-2020082026-A1 | ORGANOSILANES FOR THE TREATMENT OF INFECTIONS | TOPIKOS PHARMACEUTICALS, INC. (US) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253607-A1 | ORGANOSILANES FOR THE TREATMENT OF INFECTIONS | ASNS, ACMSD, ARG1 | BBOX1 2621/4885GMNN 808/4885ALDH1A1 1902/4885 |
| US-12180239-B2 | Organosilanes for the treatment of infections | ASNS, ACMSD, ARG1 | BBOX1 2621/4885GMNN 808/4885ALDH1A1 1902/4885 |
| US-20250304604-A1 | ORGANOSILANES FOR THE TREATMENT OF INFECTIONS | ASNS, ACMSD, ARG1 | BBOX1 2621/4885GMNN 808/4885ALDH1A1 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.